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Functionalized Platinum Nanoparticles with Biomedical Applications
Functionalized platinum nanoparticles have been of considerable interest in recent research due to their properties and applications, among which they stand out as therapeutic agents. The functionalization of the surfaces of nanoparticles can overcome the limits of medicine by increasing selectivity...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409011/ https://www.ncbi.nlm.nih.gov/pubmed/36012670 http://dx.doi.org/10.3390/ijms23169404 |
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author | Gutiérrez de la Rosa, Sagrario Yadira Muñiz Diaz, Ramiro Villalobos Gutiérrez, Paola Trinidad Patakfalvi, Rita Gutiérrez Coronado, Óscar |
author_facet | Gutiérrez de la Rosa, Sagrario Yadira Muñiz Diaz, Ramiro Villalobos Gutiérrez, Paola Trinidad Patakfalvi, Rita Gutiérrez Coronado, Óscar |
author_sort | Gutiérrez de la Rosa, Sagrario Yadira |
collection | PubMed |
description | Functionalized platinum nanoparticles have been of considerable interest in recent research due to their properties and applications, among which they stand out as therapeutic agents. The functionalization of the surfaces of nanoparticles can overcome the limits of medicine by increasing selectivity and thereby reducing the side effects of conventional drugs. With the constant development of nanotechnology in the biomedical field, functionalized platinum nanoparticles have been used to diagnose and treat diseases such as cancer and infections caused by pathogens. This review reports on physical, chemical, and biological methods of obtaining platinum nanoparticles and the advantages and disadvantages of their synthesis. Additionally, applications in the biomedical field that can be utilized once the surfaces of nanoparticles have been functionalized with different bioactive molecules are discussed, among which antibodies, biodegradable polymers, and biomolecules stand out. |
format | Online Article Text |
id | pubmed-9409011 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-94090112022-08-26 Functionalized Platinum Nanoparticles with Biomedical Applications Gutiérrez de la Rosa, Sagrario Yadira Muñiz Diaz, Ramiro Villalobos Gutiérrez, Paola Trinidad Patakfalvi, Rita Gutiérrez Coronado, Óscar Int J Mol Sci Review Functionalized platinum nanoparticles have been of considerable interest in recent research due to their properties and applications, among which they stand out as therapeutic agents. The functionalization of the surfaces of nanoparticles can overcome the limits of medicine by increasing selectivity and thereby reducing the side effects of conventional drugs. With the constant development of nanotechnology in the biomedical field, functionalized platinum nanoparticles have been used to diagnose and treat diseases such as cancer and infections caused by pathogens. This review reports on physical, chemical, and biological methods of obtaining platinum nanoparticles and the advantages and disadvantages of their synthesis. Additionally, applications in the biomedical field that can be utilized once the surfaces of nanoparticles have been functionalized with different bioactive molecules are discussed, among which antibodies, biodegradable polymers, and biomolecules stand out. MDPI 2022-08-20 /pmc/articles/PMC9409011/ /pubmed/36012670 http://dx.doi.org/10.3390/ijms23169404 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Gutiérrez de la Rosa, Sagrario Yadira Muñiz Diaz, Ramiro Villalobos Gutiérrez, Paola Trinidad Patakfalvi, Rita Gutiérrez Coronado, Óscar Functionalized Platinum Nanoparticles with Biomedical Applications |
title | Functionalized Platinum Nanoparticles with Biomedical Applications |
title_full | Functionalized Platinum Nanoparticles with Biomedical Applications |
title_fullStr | Functionalized Platinum Nanoparticles with Biomedical Applications |
title_full_unstemmed | Functionalized Platinum Nanoparticles with Biomedical Applications |
title_short | Functionalized Platinum Nanoparticles with Biomedical Applications |
title_sort | functionalized platinum nanoparticles with biomedical applications |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409011/ https://www.ncbi.nlm.nih.gov/pubmed/36012670 http://dx.doi.org/10.3390/ijms23169404 |
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