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Hepatocyte Growth Factor Enhances Antineoplastic Effect of 5-Fluorouracil by Increasing UPP1 Expression in HepG2 Cells

Aberrant activation of hepatocyte growth factor (HGF) and its receptor c-Met axis promotes tumor growth. Therefore, many clinical trials have been conducted. A phase 3 trial investigating a monoclonal antibody targeting HGF in combination with fluoropyrimidine-based chemotherapy had to be terminated...

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Detalles Bibliográficos
Autores principales:	Okumura, Manabu, Iwakiri, Tomomi, Yoshikawa, Naoki, Nagatomo, Takao, Ayabe, Takanori, Tsuneyoshi, Isao, Ikeda, Ryuji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409026/ https://www.ncbi.nlm.nih.gov/pubmed/36012373 http://dx.doi.org/10.3390/ijms23169108

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