Type 2 Diabetes Induces a Pro-Oxidative Environment in Rat Epididymis by Disrupting SIRT1/PGC-1α/SIRT3 Pathway

Diabetes mellitus type 2 (T2DM) has been associated with alterations in the male reproductive tract, especially in the epididymis. Although it is known that T2DM alters epididymal physiology, disturbing mitochondrial function and favoring oxidative stress, the mechanisms remain unknown. Sirtuin 1 (S...

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Detalles Bibliográficos
Autores principales: Diniz, Antónia, Alves, Marco G., Candeias, Emanuel, Duarte, Ana I., Moreira, Paula I., Silva, Branca M., Oliveira, Pedro F., Rato, Luís
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409047/
https://www.ncbi.nlm.nih.gov/pubmed/36012191
http://dx.doi.org/10.3390/ijms23168912

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409047/
https://www.ncbi.nlm.nih.gov/pubmed/36012191
http://dx.doi.org/10.3390/ijms23168912

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