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Type 2 Diabetes Induces a Pro-Oxidative Environment in Rat Epididymis by Disrupting SIRT1/PGC-1α/SIRT3 Pathway
Diabetes mellitus type 2 (T2DM) has been associated with alterations in the male reproductive tract, especially in the epididymis. Although it is known that T2DM alters epididymal physiology, disturbing mitochondrial function and favoring oxidative stress, the mechanisms remain unknown. Sirtuin 1 (S...
Autores principales: | Diniz, Antónia, Alves, Marco G., Candeias, Emanuel, Duarte, Ana I., Moreira, Paula I., Silva, Branca M., Oliveira, Pedro F., Rato, Luís |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409047/ https://www.ncbi.nlm.nih.gov/pubmed/36012191 http://dx.doi.org/10.3390/ijms23168912 |
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