Cargando…

Fabrication, Characterization, and Antimicrobial Activity of Carvacrol-Loaded Zein Nanoparticles Using the pH-Driven Method

To reduce the application of synthetic additives in the field of food preservation, this study utilized carvacrol as an antibacterial agent, and zein and sodium caseinate as carriers, to prepare composite nanoparticles loaded with carvacrol by the pH-driven method. The composite nanoparticles of zei...

Descripción completa

Detalles Bibliográficos
Autores principales: Zheng, Huaming, Wang, Jiangli, You, Feng, Zhou, Mingyu, Shi, Shengwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409059/
https://www.ncbi.nlm.nih.gov/pubmed/36012491
http://dx.doi.org/10.3390/ijms23169227
_version_ 1784774756965285888
author Zheng, Huaming
Wang, Jiangli
You, Feng
Zhou, Mingyu
Shi, Shengwei
author_facet Zheng, Huaming
Wang, Jiangli
You, Feng
Zhou, Mingyu
Shi, Shengwei
author_sort Zheng, Huaming
collection PubMed
description To reduce the application of synthetic additives in the field of food preservation, this study utilized carvacrol as an antibacterial agent, and zein and sodium caseinate as carriers, to prepare composite nanoparticles loaded with carvacrol by the pH-driven method. The composite nanoparticles of zein/sodium caseinate had an excellent encapsulation efficiency (77.96~82.19%) for carvacrol, and it had remarkable redispersibility. The results of Fourier transform infrared spectroscopy showed that the formation of the composite nanoparticles mainly depended on the hydrogen bond and the hydrophobic zone force, and thermal gravimetric analysis showed that carvacrol was loaded successfully into nanoparticles, and loading efficiency reached 24.9%. Scanning electron microscopy showed that the composite nanoparticles were spherical, with a particle size range of 50~200 nm, and through the free radical scavenging method and the plate counting method to confirm the particle has stronger antioxidant and antibacterial properties, and with the composite nanoparticles with poly (vinyl alcohol) film applied to the preservation of banana together, it was found that PVA film containing 5 wt% CA-loaded composite NPs can significantly extend the storage period of banana. Therefore, when the composite nanoparticles were applied to food packaging, they could effectively inhibit food spoilage and lengthen the shelf life of food, which displays potential application prospects in the food industry.
format Online
Article
Text
id pubmed-9409059
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-94090592022-08-26 Fabrication, Characterization, and Antimicrobial Activity of Carvacrol-Loaded Zein Nanoparticles Using the pH-Driven Method Zheng, Huaming Wang, Jiangli You, Feng Zhou, Mingyu Shi, Shengwei Int J Mol Sci Article To reduce the application of synthetic additives in the field of food preservation, this study utilized carvacrol as an antibacterial agent, and zein and sodium caseinate as carriers, to prepare composite nanoparticles loaded with carvacrol by the pH-driven method. The composite nanoparticles of zein/sodium caseinate had an excellent encapsulation efficiency (77.96~82.19%) for carvacrol, and it had remarkable redispersibility. The results of Fourier transform infrared spectroscopy showed that the formation of the composite nanoparticles mainly depended on the hydrogen bond and the hydrophobic zone force, and thermal gravimetric analysis showed that carvacrol was loaded successfully into nanoparticles, and loading efficiency reached 24.9%. Scanning electron microscopy showed that the composite nanoparticles were spherical, with a particle size range of 50~200 nm, and through the free radical scavenging method and the plate counting method to confirm the particle has stronger antioxidant and antibacterial properties, and with the composite nanoparticles with poly (vinyl alcohol) film applied to the preservation of banana together, it was found that PVA film containing 5 wt% CA-loaded composite NPs can significantly extend the storage period of banana. Therefore, when the composite nanoparticles were applied to food packaging, they could effectively inhibit food spoilage and lengthen the shelf life of food, which displays potential application prospects in the food industry. MDPI 2022-08-17 /pmc/articles/PMC9409059/ /pubmed/36012491 http://dx.doi.org/10.3390/ijms23169227 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Zheng, Huaming
Wang, Jiangli
You, Feng
Zhou, Mingyu
Shi, Shengwei
Fabrication, Characterization, and Antimicrobial Activity of Carvacrol-Loaded Zein Nanoparticles Using the pH-Driven Method
title Fabrication, Characterization, and Antimicrobial Activity of Carvacrol-Loaded Zein Nanoparticles Using the pH-Driven Method
title_full Fabrication, Characterization, and Antimicrobial Activity of Carvacrol-Loaded Zein Nanoparticles Using the pH-Driven Method
title_fullStr Fabrication, Characterization, and Antimicrobial Activity of Carvacrol-Loaded Zein Nanoparticles Using the pH-Driven Method
title_full_unstemmed Fabrication, Characterization, and Antimicrobial Activity of Carvacrol-Loaded Zein Nanoparticles Using the pH-Driven Method
title_short Fabrication, Characterization, and Antimicrobial Activity of Carvacrol-Loaded Zein Nanoparticles Using the pH-Driven Method
title_sort fabrication, characterization, and antimicrobial activity of carvacrol-loaded zein nanoparticles using the ph-driven method
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409059/
https://www.ncbi.nlm.nih.gov/pubmed/36012491
http://dx.doi.org/10.3390/ijms23169227
work_keys_str_mv AT zhenghuaming fabricationcharacterizationandantimicrobialactivityofcarvacrolloadedzeinnanoparticlesusingthephdrivenmethod
AT wangjiangli fabricationcharacterizationandantimicrobialactivityofcarvacrolloadedzeinnanoparticlesusingthephdrivenmethod
AT youfeng fabricationcharacterizationandantimicrobialactivityofcarvacrolloadedzeinnanoparticlesusingthephdrivenmethod
AT zhoumingyu fabricationcharacterizationandantimicrobialactivityofcarvacrolloadedzeinnanoparticlesusingthephdrivenmethod
AT shishengwei fabricationcharacterizationandantimicrobialactivityofcarvacrolloadedzeinnanoparticlesusingthephdrivenmethod