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Experimental Autoimmune Encephalomyelitis of Mice: Enzymatic Cross Site-Specific Hydrolysis of H4 Histone by IgGs against Histones and Myelin Basic Protein

Histones play vital roles in chromatin functioning and gene transcription, but in intercellular space, they are harmful due to stimulating systemic inflammatory and toxic responses. Myelin basic protein (MBP) is the most important protein of the axon myelin–proteolipid sheath. Antibodies-abzymes wit...

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Detalles Bibliográficos
Autores principales:	Urusov, Andrey E., Aulova, Kseniya S., Dmitrenok, Pavel S., Buneva, Valentina N., Nevinsky, Georgy A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409114/ https://www.ncbi.nlm.nih.gov/pubmed/36012448 http://dx.doi.org/10.3390/ijms23169182

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