Transcriptomic Analysis of Human Fragile X Syndrome Neurons Reveals Neurite Outgrowth Modulation by the TGFβ/BMP Pathway

Fragile X Syndrome (FXS) is the main genetic reason for intellectual disability and is caused by the silencing of fragile X mental retardation protein (FMRP), an RNA-binding protein regulating the translation of many neuronal mRNAs. Neural differentiation of FX human embryonic stem cells (hESC) mimi...

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Detalles Bibliográficos
Autores principales: Kuznitsov-Yanovsky, Liron, Shapira, Guy, Gildin, Lital, Shomron, Noam, Ben-Yosef, Dalit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409179/
https://www.ncbi.nlm.nih.gov/pubmed/36012539
http://dx.doi.org/10.3390/ijms23169278

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