A Novel Drug Modulator Diarylheptanoid (trans-1,7-Diphenyl-5-hydroxy-1-heptene) from Curcuma comosa Rhizomes for P-glycoprotein Function and Apoptosis Induction in K652/ADR Leukemic Cells

Curcuma comosa has been used in traditional Thai medicine to treat menstrual cycle-related symptoms in women. This study aims to evaluate the diarylheptanoid drug modulator, trans-1,7-diphenyl-5-hydroxy-1-heptene (DHH), in drug-resistant K562/ADR human leukemic cells. This compound was studied due t...

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Detalles Bibliográficos
Autores principales: Viriyaadhammaa, Natsima, Duangmano, Suwit, Saiai, Aroonchai, Tungjai, Montree, Dejkriengkraikul, Pornngarm, Tima, Singkome, Chiampanichayakul, Sawitree, Krise, Jeffrey, Anuchapreeda, Songyot
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409401/
https://www.ncbi.nlm.nih.gov/pubmed/36012254
http://dx.doi.org/10.3390/ijms23168989

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