Functional Crosstalk between PCSK9 Internalization and Pro-Inflammatory Activation in Human Macrophages: Role of Reactive Oxygen Species Release

Atherosclerosis is a cardiovascular disease caused mainly by dyslipidemia and is characterized by the formation of an atheroma plaque and chronic inflammation. Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a protease that induces the degradation of the LDL receptor (LDLR), which contribut...

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Detalles Bibliográficos
Autores principales: Jaén, Rafael I., Povo-Retana, Adrián, Rosales-Mendoza, César, Capillas-Herrero, Patricia, Sánchez-García, Sergio, Martín-Sanz, Paloma, Mojena, Marina, Prieto, Patricia, Boscá, Lisardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409451/
https://www.ncbi.nlm.nih.gov/pubmed/36012389
http://dx.doi.org/10.3390/ijms23169114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409451/
https://www.ncbi.nlm.nih.gov/pubmed/36012389
http://dx.doi.org/10.3390/ijms23169114

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