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Combined Treatment of Bronchial Epithelial Calu-3 Cells with Peptide Nucleic Acids Targeting miR-145-5p and miR-101-3p: Synergistic Enhancement of the Expression of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Gene

The Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene encodes for a chloride channel defective in Cystic Fibrosis (CF). Accordingly, upregulation of its expression might be relevant for the development of therapeutic protocols for CF. MicroRNAs are deeply involved in the CFTR regulatio...

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Detalles Bibliográficos
Autores principales:	Papi, Chiara, Gasparello, Jessica, Zurlo, Matteo, Manicardi, Alex, Corradini, Roberto, Cabrini, Giulio, Gambari, Roberto, Finotti, Alessia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Brief Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409490/ https://www.ncbi.nlm.nih.gov/pubmed/36012615 http://dx.doi.org/10.3390/ijms23169348

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