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High activity of an affinity-matured ACE2 decoy against Omicron SARS-CoV-2 and pre-emergent coronaviruses

The viral genome of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), particularly its cell-binding spike protein gene, has undergone rapid evolution during the coronavirus disease 2019 (COVID-19) pandemic. Variants including Omicron BA.1 and Omicron BA.2 now seriously threaten the effic...

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Detalles Bibliográficos
Autores principales: Sims, Joshua J., Lian, Sharon, Meggersee, Rosemary L., Kasimsetty, Aradhana, Wilson, James M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409550/
https://www.ncbi.nlm.nih.gov/pubmed/36006993
http://dx.doi.org/10.1371/journal.pone.0271359

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