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Human alveolar progenitors generate dual lineage bronchioalveolar organoids

Mechanisms of epithelial renewal in the alveolar compartment remain incompletely understood. To this end, we aimed to characterize alveolar progenitors. Single-cell RNA-sequencing (scRNA-seq) analysis of the HTII-280(+)/EpCAM(+) population from adult human lung revealed subclusters enriched for adul...

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Detalles Bibliográficos
Autores principales: Hoffmann, Karen, Obermayer, Benedikt, Hönzke, Katja, Fatykhova, Diana, Demir, Zeynep, Löwa, Anna, Alves, Luiz Gustavo Teixeira, Wyler, Emanuel, Lopez-Rodriguez, Elena, Mieth, Maren, Baumgardt, Morris, Hoppe, Judith, Firsching, Theresa C., Tönnies, Mario, Bauer, Torsten T., Eggeling, Stephan, Tran, Hong-Linh, Schneider, Paul, Neudecker, Jens, Rückert, Jens C., Gruber, Achim D., Ochs, Matthias, Landthaler, Markus, Beule, Dieter, Suttorp, Norbert, Hippenstiel, Stefan, Hocke, Andreas C., Kessler, Mirjana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409623/
https://www.ncbi.nlm.nih.gov/pubmed/36008580
http://dx.doi.org/10.1038/s42003-022-03828-5

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