Cargando…

Management of Preschool Wheezing: Guideline from the Emilia-Romagna Asthma (ERA) Study Group

Preschool wheezing should be considered an umbrella term for distinctive diseases with different observable and measurable phenotypes. Despite many efforts, there is a large gap in knowledge regarding management of preschool wheezing. In order to fill this lack of knowledge, the aim of these guideli...

Descripción completa

Detalles Bibliográficos
Autores principales: Fainardi, Valentina, Caffarelli, Carlo, Deolmi, Michela, Skenderaj, Kaltra, Meoli, Aniello, Morini, Riccardo, Bergamini, Barbara Maria, Bertelli, Luca, Biserna, Loretta, Bottau, Paolo, Corinaldesi, Elena, De Paulis, Nicoletta, Dondi, Arianna, Guidi, Battista, Lombardi, Francesca, Magistrali, Maria Sole, Marastoni, Elisabetta, Pastorelli, Silvia, Piccorossi, Alessandra, Poloni, Maurizio, Tagliati, Sylvie, Vaienti, Francesca, Gregori, Giuseppe, Sacchetti, Roberto, Mari, Sandra, Musetti, Manuela, Antodaro, Francesco, Bergomi, Andrea, Reggiani, Lamberto, Caramelli, Fabio, De Fanti, Alessandro, Marchetti, Federico, Ricci, Giampaolo, Esposito, Susanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409690/
https://www.ncbi.nlm.nih.gov/pubmed/36013002
http://dx.doi.org/10.3390/jcm11164763
_version_ 1784774912965083136
author Fainardi, Valentina
Caffarelli, Carlo
Deolmi, Michela
Skenderaj, Kaltra
Meoli, Aniello
Morini, Riccardo
Bergamini, Barbara Maria
Bertelli, Luca
Biserna, Loretta
Bottau, Paolo
Corinaldesi, Elena
De Paulis, Nicoletta
Dondi, Arianna
Guidi, Battista
Lombardi, Francesca
Magistrali, Maria Sole
Marastoni, Elisabetta
Pastorelli, Silvia
Piccorossi, Alessandra
Poloni, Maurizio
Tagliati, Sylvie
Vaienti, Francesca
Gregori, Giuseppe
Sacchetti, Roberto
Mari, Sandra
Musetti, Manuela
Antodaro, Francesco
Bergomi, Andrea
Reggiani, Lamberto
Caramelli, Fabio
De Fanti, Alessandro
Marchetti, Federico
Ricci, Giampaolo
Esposito, Susanna
author_facet Fainardi, Valentina
Caffarelli, Carlo
Deolmi, Michela
Skenderaj, Kaltra
Meoli, Aniello
Morini, Riccardo
Bergamini, Barbara Maria
Bertelli, Luca
Biserna, Loretta
Bottau, Paolo
Corinaldesi, Elena
De Paulis, Nicoletta
Dondi, Arianna
Guidi, Battista
Lombardi, Francesca
Magistrali, Maria Sole
Marastoni, Elisabetta
Pastorelli, Silvia
Piccorossi, Alessandra
Poloni, Maurizio
Tagliati, Sylvie
Vaienti, Francesca
Gregori, Giuseppe
Sacchetti, Roberto
Mari, Sandra
Musetti, Manuela
Antodaro, Francesco
Bergomi, Andrea
Reggiani, Lamberto
Caramelli, Fabio
De Fanti, Alessandro
Marchetti, Federico
Ricci, Giampaolo
Esposito, Susanna
author_sort Fainardi, Valentina
collection PubMed
description Preschool wheezing should be considered an umbrella term for distinctive diseases with different observable and measurable phenotypes. Despite many efforts, there is a large gap in knowledge regarding management of preschool wheezing. In order to fill this lack of knowledge, the aim of these guidelines was to define management of wheezing disorders in preschool children (aged up to 5 years). A multidisciplinary panel of experts of the Emilia-Romagna Region, Italy, addressed twelve different key questions regarding the management of preschool wheezing. Clinical questions have been formulated by the expert panel using the PICO format (Patients, Intervention, Comparison, Outcomes) and systematic reviews have been conducted on PubMed to answer these specific questions, with the aim of formulating recommendations. The GRADE approach has been used for each selected paper, to assess the quality of the evidence and the degree of recommendations. These guidelines represent, in our opinion, the most complete and up-to-date collection of recommendations on preschool wheezing to guide pediatricians in the management of their patients, standardizing approaches. Undoubtedly, more research is needed to find objective biomarkers and understand underlying mechanisms to assess phenotype and endotype and to personalize targeted treatment.
format Online
Article
Text
id pubmed-9409690
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-94096902022-08-26 Management of Preschool Wheezing: Guideline from the Emilia-Romagna Asthma (ERA) Study Group Fainardi, Valentina Caffarelli, Carlo Deolmi, Michela Skenderaj, Kaltra Meoli, Aniello Morini, Riccardo Bergamini, Barbara Maria Bertelli, Luca Biserna, Loretta Bottau, Paolo Corinaldesi, Elena De Paulis, Nicoletta Dondi, Arianna Guidi, Battista Lombardi, Francesca Magistrali, Maria Sole Marastoni, Elisabetta Pastorelli, Silvia Piccorossi, Alessandra Poloni, Maurizio Tagliati, Sylvie Vaienti, Francesca Gregori, Giuseppe Sacchetti, Roberto Mari, Sandra Musetti, Manuela Antodaro, Francesco Bergomi, Andrea Reggiani, Lamberto Caramelli, Fabio De Fanti, Alessandro Marchetti, Federico Ricci, Giampaolo Esposito, Susanna J Clin Med Article Preschool wheezing should be considered an umbrella term for distinctive diseases with different observable and measurable phenotypes. Despite many efforts, there is a large gap in knowledge regarding management of preschool wheezing. In order to fill this lack of knowledge, the aim of these guidelines was to define management of wheezing disorders in preschool children (aged up to 5 years). A multidisciplinary panel of experts of the Emilia-Romagna Region, Italy, addressed twelve different key questions regarding the management of preschool wheezing. Clinical questions have been formulated by the expert panel using the PICO format (Patients, Intervention, Comparison, Outcomes) and systematic reviews have been conducted on PubMed to answer these specific questions, with the aim of formulating recommendations. The GRADE approach has been used for each selected paper, to assess the quality of the evidence and the degree of recommendations. These guidelines represent, in our opinion, the most complete and up-to-date collection of recommendations on preschool wheezing to guide pediatricians in the management of their patients, standardizing approaches. Undoubtedly, more research is needed to find objective biomarkers and understand underlying mechanisms to assess phenotype and endotype and to personalize targeted treatment. MDPI 2022-08-15 /pmc/articles/PMC9409690/ /pubmed/36013002 http://dx.doi.org/10.3390/jcm11164763 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Fainardi, Valentina
Caffarelli, Carlo
Deolmi, Michela
Skenderaj, Kaltra
Meoli, Aniello
Morini, Riccardo
Bergamini, Barbara Maria
Bertelli, Luca
Biserna, Loretta
Bottau, Paolo
Corinaldesi, Elena
De Paulis, Nicoletta
Dondi, Arianna
Guidi, Battista
Lombardi, Francesca
Magistrali, Maria Sole
Marastoni, Elisabetta
Pastorelli, Silvia
Piccorossi, Alessandra
Poloni, Maurizio
Tagliati, Sylvie
Vaienti, Francesca
Gregori, Giuseppe
Sacchetti, Roberto
Mari, Sandra
Musetti, Manuela
Antodaro, Francesco
Bergomi, Andrea
Reggiani, Lamberto
Caramelli, Fabio
De Fanti, Alessandro
Marchetti, Federico
Ricci, Giampaolo
Esposito, Susanna
Management of Preschool Wheezing: Guideline from the Emilia-Romagna Asthma (ERA) Study Group
title Management of Preschool Wheezing: Guideline from the Emilia-Romagna Asthma (ERA) Study Group
title_full Management of Preschool Wheezing: Guideline from the Emilia-Romagna Asthma (ERA) Study Group
title_fullStr Management of Preschool Wheezing: Guideline from the Emilia-Romagna Asthma (ERA) Study Group
title_full_unstemmed Management of Preschool Wheezing: Guideline from the Emilia-Romagna Asthma (ERA) Study Group
title_short Management of Preschool Wheezing: Guideline from the Emilia-Romagna Asthma (ERA) Study Group
title_sort management of preschool wheezing: guideline from the emilia-romagna asthma (era) study group
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409690/
https://www.ncbi.nlm.nih.gov/pubmed/36013002
http://dx.doi.org/10.3390/jcm11164763
work_keys_str_mv AT fainardivalentina managementofpreschoolwheezingguidelinefromtheemiliaromagnaasthmaerastudygroup
AT caffarellicarlo managementofpreschoolwheezingguidelinefromtheemiliaromagnaasthmaerastudygroup
AT deolmimichela managementofpreschoolwheezingguidelinefromtheemiliaromagnaasthmaerastudygroup
AT skenderajkaltra managementofpreschoolwheezingguidelinefromtheemiliaromagnaasthmaerastudygroup
AT meolianiello managementofpreschoolwheezingguidelinefromtheemiliaromagnaasthmaerastudygroup
AT moriniriccardo managementofpreschoolwheezingguidelinefromtheemiliaromagnaasthmaerastudygroup
AT bergaminibarbaramaria managementofpreschoolwheezingguidelinefromtheemiliaromagnaasthmaerastudygroup
AT bertelliluca managementofpreschoolwheezingguidelinefromtheemiliaromagnaasthmaerastudygroup
AT bisernaloretta managementofpreschoolwheezingguidelinefromtheemiliaromagnaasthmaerastudygroup
AT bottaupaolo managementofpreschoolwheezingguidelinefromtheemiliaromagnaasthmaerastudygroup
AT corinaldesielena managementofpreschoolwheezingguidelinefromtheemiliaromagnaasthmaerastudygroup
AT depaulisnicoletta managementofpreschoolwheezingguidelinefromtheemiliaromagnaasthmaerastudygroup
AT dondiarianna managementofpreschoolwheezingguidelinefromtheemiliaromagnaasthmaerastudygroup
AT guidibattista managementofpreschoolwheezingguidelinefromtheemiliaromagnaasthmaerastudygroup
AT lombardifrancesca managementofpreschoolwheezingguidelinefromtheemiliaromagnaasthmaerastudygroup
AT magistralimariasole managementofpreschoolwheezingguidelinefromtheemiliaromagnaasthmaerastudygroup
AT marastonielisabetta managementofpreschoolwheezingguidelinefromtheemiliaromagnaasthmaerastudygroup
AT pastorellisilvia managementofpreschoolwheezingguidelinefromtheemiliaromagnaasthmaerastudygroup
AT piccorossialessandra managementofpreschoolwheezingguidelinefromtheemiliaromagnaasthmaerastudygroup
AT polonimaurizio managementofpreschoolwheezingguidelinefromtheemiliaromagnaasthmaerastudygroup
AT tagliatisylvie managementofpreschoolwheezingguidelinefromtheemiliaromagnaasthmaerastudygroup
AT vaientifrancesca managementofpreschoolwheezingguidelinefromtheemiliaromagnaasthmaerastudygroup
AT gregorigiuseppe managementofpreschoolwheezingguidelinefromtheemiliaromagnaasthmaerastudygroup
AT sacchettiroberto managementofpreschoolwheezingguidelinefromtheemiliaromagnaasthmaerastudygroup
AT marisandra managementofpreschoolwheezingguidelinefromtheemiliaromagnaasthmaerastudygroup
AT musettimanuela managementofpreschoolwheezingguidelinefromtheemiliaromagnaasthmaerastudygroup
AT antodarofrancesco managementofpreschoolwheezingguidelinefromtheemiliaromagnaasthmaerastudygroup
AT bergomiandrea managementofpreschoolwheezingguidelinefromtheemiliaromagnaasthmaerastudygroup
AT reggianilamberto managementofpreschoolwheezingguidelinefromtheemiliaromagnaasthmaerastudygroup
AT caramellifabio managementofpreschoolwheezingguidelinefromtheemiliaromagnaasthmaerastudygroup
AT defantialessandro managementofpreschoolwheezingguidelinefromtheemiliaromagnaasthmaerastudygroup
AT marchettifederico managementofpreschoolwheezingguidelinefromtheemiliaromagnaasthmaerastudygroup
AT riccigiampaolo managementofpreschoolwheezingguidelinefromtheemiliaromagnaasthmaerastudygroup
AT espositosusanna managementofpreschoolwheezingguidelinefromtheemiliaromagnaasthmaerastudygroup