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The Repertoire of Tissue Inhibitors of Metalloproteases: Evolution, Regulation of Extracellular Matrix Proteolysis, Engineering and Therapeutic Challenges

Tissue inhibitors of metalloproteases (TIMPs) belong to a fascinating protein family expressed in all Metazoa. They act as regulators of the turnover of the extracellular matrix, and they are consistently involved in essential processes. Herein, we recapitulate the main activities of mammalian TIMPs...

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Detalles Bibliográficos
Autores principales:	Costa, Salvatore, Ragusa, Maria Antonietta, Lo Buglio, Gabriele, Scilabra, Simone Dario, Nicosia, Aldo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409782/ https://www.ncbi.nlm.nih.gov/pubmed/36013323 http://dx.doi.org/10.3390/life12081145

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