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Long-Term Follow-Up of Patients Diagnosed with COVID-19-Associated Pulmonary Aspergillosis (CAPA)

COVID-19-associated pulmonary aspergillosis (CAPA) have been documented during the COVID-19 pandemic. The vast majority of these patients do not meet the classic EORTC/MSGERC criteria for invasive pulmonary aspergillosis. The question arises as to whether there may have been an over-diagnosis of thi...

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Autores principales: Ruiz-Ruigómez, María, Fernández-Ruiz, Mario, Pérez-Ayala, Ana, Aguado, José María
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409906/
https://www.ncbi.nlm.nih.gov/pubmed/36012828
http://dx.doi.org/10.3390/jof8080840
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author Ruiz-Ruigómez, María
Fernández-Ruiz, Mario
Pérez-Ayala, Ana
Aguado, José María
author_facet Ruiz-Ruigómez, María
Fernández-Ruiz, Mario
Pérez-Ayala, Ana
Aguado, José María
author_sort Ruiz-Ruigómez, María
collection PubMed
description COVID-19-associated pulmonary aspergillosis (CAPA) have been documented during the COVID-19 pandemic. The vast majority of these patients do not meet the classic EORTC/MSGERC criteria for invasive pulmonary aspergillosis. The question arises as to whether there may have been an over-diagnosis of this disease. Here we review our experience and analyze the evolution of 27 patients who were diagnosed with CAPA during hospital admission. Surviving patients were followed-up for a mean time of 15 months (SD 3.78) by a group of experts and clinical records of diseased patients were reviewed. After expert evaluation and follow-up, 10 patients were finally assumed as CAPA according to expert opinion. These cases represent 40% of the initially CAPA assumed cases. Our data suggest the need to reconsider actual diagnosis criteria for CAPA what could drive to better identification of these patients.
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spelling pubmed-94099062022-08-26 Long-Term Follow-Up of Patients Diagnosed with COVID-19-Associated Pulmonary Aspergillosis (CAPA) Ruiz-Ruigómez, María Fernández-Ruiz, Mario Pérez-Ayala, Ana Aguado, José María J Fungi (Basel) Brief Report COVID-19-associated pulmonary aspergillosis (CAPA) have been documented during the COVID-19 pandemic. The vast majority of these patients do not meet the classic EORTC/MSGERC criteria for invasive pulmonary aspergillosis. The question arises as to whether there may have been an over-diagnosis of this disease. Here we review our experience and analyze the evolution of 27 patients who were diagnosed with CAPA during hospital admission. Surviving patients were followed-up for a mean time of 15 months (SD 3.78) by a group of experts and clinical records of diseased patients were reviewed. After expert evaluation and follow-up, 10 patients were finally assumed as CAPA according to expert opinion. These cases represent 40% of the initially CAPA assumed cases. Our data suggest the need to reconsider actual diagnosis criteria for CAPA what could drive to better identification of these patients. MDPI 2022-08-11 /pmc/articles/PMC9409906/ /pubmed/36012828 http://dx.doi.org/10.3390/jof8080840 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Brief Report
Ruiz-Ruigómez, María
Fernández-Ruiz, Mario
Pérez-Ayala, Ana
Aguado, José María
Long-Term Follow-Up of Patients Diagnosed with COVID-19-Associated Pulmonary Aspergillosis (CAPA)
title Long-Term Follow-Up of Patients Diagnosed with COVID-19-Associated Pulmonary Aspergillosis (CAPA)
title_full Long-Term Follow-Up of Patients Diagnosed with COVID-19-Associated Pulmonary Aspergillosis (CAPA)
title_fullStr Long-Term Follow-Up of Patients Diagnosed with COVID-19-Associated Pulmonary Aspergillosis (CAPA)
title_full_unstemmed Long-Term Follow-Up of Patients Diagnosed with COVID-19-Associated Pulmonary Aspergillosis (CAPA)
title_short Long-Term Follow-Up of Patients Diagnosed with COVID-19-Associated Pulmonary Aspergillosis (CAPA)
title_sort long-term follow-up of patients diagnosed with covid-19-associated pulmonary aspergillosis (capa)
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409906/
https://www.ncbi.nlm.nih.gov/pubmed/36012828
http://dx.doi.org/10.3390/jof8080840
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