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The Efficacy of DW and T1-W MRI Combined with CT in the Preoperative Evaluation of Cholesteatoma
Objective: This study aims to assess the efficacy of diffusion-weighted (DW) and T1-weighted (T1W) magnetic resonance imaging (MRI) combined with high-resolution computed tomography (HRCT) (together as DW-T1W-CT) in the preoperative evaluation of the presence and extent of cholesteatoma, which helps...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409941/ https://www.ncbi.nlm.nih.gov/pubmed/36013298 http://dx.doi.org/10.3390/jpm12081349 |
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author | Sun, Wan-Hsuan Fan, Jiun-Kai Huang, Tzu-Chin |
author_facet | Sun, Wan-Hsuan Fan, Jiun-Kai Huang, Tzu-Chin |
author_sort | Sun, Wan-Hsuan |
collection | PubMed |
description | Objective: This study aims to assess the efficacy of diffusion-weighted (DW) and T1-weighted (T1W) magnetic resonance imaging (MRI) combined with high-resolution computed tomography (HRCT) (together as DW-T1W-CT) in the preoperative evaluation of the presence and extent of cholesteatoma, which helps determine whether a patient is suitable for transcanal endoscopic ear surgery (TEES). Methods: This retrospective study included 35 patients (18 male and 17 female) aged from 2 to 81 years diagnosed with chronic otitis media with or without cholesteatoma, who had received surgical treatment and a preoperative MRI and HRCT during the period of December 2015 to December 2020 at Cathay General Hospital. We compared the preoperative DW-T1W-CT findings with the intraoperative findings and final pathologic diagnosis. The accurate predictive value was evaluated using the presence of cholesteatoma and its extent. Results: Regarding the efficacy of detecting cholesteatoma, we found a sensitivity of 92% (23/25 cases with cholesteatoma), a specificity of 90% (9/10 cases without cholesteatoma), and an overall accurate predictive value of 91.4% (32/35) by using combined DW-T1W-CT imaging. With regard to evaluating the extent of cholesteatoma, the combined DW-T1W-CT images obtained an accurate predictive value of 84% (21/25 cases of cholesteatoma). Conclusion: Combined DW-T1W-CT has been proven to be a reliable tool in detecting the presence of cholesteatoma. It is also useful in preoperatively depicting the extent of cholesteatoma, which is crucial for determining whether a patient is suitable for TEES, aiding in surgical planning and patient consultation. |
format | Online Article Text |
id | pubmed-9409941 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-94099412022-08-26 The Efficacy of DW and T1-W MRI Combined with CT in the Preoperative Evaluation of Cholesteatoma Sun, Wan-Hsuan Fan, Jiun-Kai Huang, Tzu-Chin J Pers Med Article Objective: This study aims to assess the efficacy of diffusion-weighted (DW) and T1-weighted (T1W) magnetic resonance imaging (MRI) combined with high-resolution computed tomography (HRCT) (together as DW-T1W-CT) in the preoperative evaluation of the presence and extent of cholesteatoma, which helps determine whether a patient is suitable for transcanal endoscopic ear surgery (TEES). Methods: This retrospective study included 35 patients (18 male and 17 female) aged from 2 to 81 years diagnosed with chronic otitis media with or without cholesteatoma, who had received surgical treatment and a preoperative MRI and HRCT during the period of December 2015 to December 2020 at Cathay General Hospital. We compared the preoperative DW-T1W-CT findings with the intraoperative findings and final pathologic diagnosis. The accurate predictive value was evaluated using the presence of cholesteatoma and its extent. Results: Regarding the efficacy of detecting cholesteatoma, we found a sensitivity of 92% (23/25 cases with cholesteatoma), a specificity of 90% (9/10 cases without cholesteatoma), and an overall accurate predictive value of 91.4% (32/35) by using combined DW-T1W-CT imaging. With regard to evaluating the extent of cholesteatoma, the combined DW-T1W-CT images obtained an accurate predictive value of 84% (21/25 cases of cholesteatoma). Conclusion: Combined DW-T1W-CT has been proven to be a reliable tool in detecting the presence of cholesteatoma. It is also useful in preoperatively depicting the extent of cholesteatoma, which is crucial for determining whether a patient is suitable for TEES, aiding in surgical planning and patient consultation. MDPI 2022-08-21 /pmc/articles/PMC9409941/ /pubmed/36013298 http://dx.doi.org/10.3390/jpm12081349 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Sun, Wan-Hsuan Fan, Jiun-Kai Huang, Tzu-Chin The Efficacy of DW and T1-W MRI Combined with CT in the Preoperative Evaluation of Cholesteatoma |
title | The Efficacy of DW and T1-W MRI Combined with CT in the Preoperative Evaluation of Cholesteatoma |
title_full | The Efficacy of DW and T1-W MRI Combined with CT in the Preoperative Evaluation of Cholesteatoma |
title_fullStr | The Efficacy of DW and T1-W MRI Combined with CT in the Preoperative Evaluation of Cholesteatoma |
title_full_unstemmed | The Efficacy of DW and T1-W MRI Combined with CT in the Preoperative Evaluation of Cholesteatoma |
title_short | The Efficacy of DW and T1-W MRI Combined with CT in the Preoperative Evaluation of Cholesteatoma |
title_sort | efficacy of dw and t1-w mri combined with ct in the preoperative evaluation of cholesteatoma |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9409941/ https://www.ncbi.nlm.nih.gov/pubmed/36013298 http://dx.doi.org/10.3390/jpm12081349 |
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