Formulation, Characterization, and In Vitro/In Vivo Efficacy Studies of a Novel Liposomal Drug Delivery System of Amphiphilic Jaspine B for Treatment of Synovial Sarcoma

Sphingomyelin is a cell membrane sphingolipid that is upregulated in synovial sarcoma (SS). Jaspine B has been shown to inhibit sphingomyelin synthase, which synthesizes sphingomyelin from ceramide, a critical signal transducer; however, jaspine B’s low bioavailability limits its application as a pr...

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Detalles Bibliográficos
Autores principales: Khajeh pour, Sana, Mateen, Sameena, Pashikanti, Srinath, Barrott, Jared J., Aghazadeh-Habashi, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410108/
https://www.ncbi.nlm.nih.gov/pubmed/36005512
http://dx.doi.org/10.3390/md20080509

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