Cryptococcus neoformans Prp8 Intein: An In Vivo Target-Based Drug Screening System in Saccharomyces cerevisiae to Identify Protein Splicing Inhibitors and Explore Its Dynamics

Inteins are genetic mobile elements that are inserted within protein-coding genes, which are usually housekeeping genes. They are transcribed and translated along with the host gene, then catalyze their own splicing out of the host protein, which assumes its functional conformation thereafter. As Pr...

Descripción completa

Detalles Bibliográficos
Autores principales: Fernandes, José Alex Lourenço, Zatti, Matheus da Silva, Arantes, Thales Domingos, de Souza, Maria Fernanda Bezerra, Santoni, Mariana Marchi, Rossi, Danuza, Zanelli, Cleslei Fernando, Liu, Xiang-Qin, Bagagli, Eduardo, Theodoro, Raquel Cordeiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410109/
https://www.ncbi.nlm.nih.gov/pubmed/36012834
http://dx.doi.org/10.3390/jof8080846

Ejemplares similares

Ejemplares similares