Cargando…
Antibody-Drug Conjugates Containing Payloads from Marine Origin
Antibody-drug conjugates (ADCs) are an important class of therapeutics for the treatment of cancer. Structurally, an ADC comprises an antibody, which serves as the delivery system, a payload drug that is a potent cytotoxin that kills cancer cells, and a chemical linker that connects the payload with...
Autores principales: | Cheng-Sánchez, Iván, Moya-Utrera, Federico, Porras-Alcalá, Cristina, López-Romero, Juan M., Sarabia, Francisco |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410405/ https://www.ncbi.nlm.nih.gov/pubmed/36005497 http://dx.doi.org/10.3390/md20080494 |
Ejemplares similares
-
Antibody–drug conjugates: Recent advances in payloads
por: Wang, Zhijia, et al.
Publicado: (2023) -
Nicotinamide Phosphoribosyltransferase Inhibitor as
a Novel Payload for Antibody–Drug Conjugates
por: Karpov, Alexei S., et al.
Publicado: (2018) -
Site-Specific Antibody Conjugation with Payloads beyond Cytotoxins
por: Zhou, Qun
Publicado: (2023) -
Payload diversification: a key step in the development of antibody–drug conjugates
por: Conilh, Louise, et al.
Publicado: (2023) -
Disulfide re-bridging reagents for single-payload antibody-drug conjugates
por: King, Thomas A., et al.
Publicado: (2023)