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ABO Blood Group in Relation to COVID-19 Susceptibility and Clinical Outcomes: A Retrospective Observational Study in the United Arab Emirates

(1) Background: The association between ABO blood groups and COVID-19 outcomes was investigated in several studies. The results were controversial. This study aimed to explore the association between ABO blood groups and COVID-19 outcomes. (2) Methods: This retrospective study included 303 COVID-19...

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Autores principales: Hafez, Wael, Ahmed, Shougyat, Abbas, Nihad, Ahmed, Kamran, Kamran, Samera, Arya, Arun, Rao, Srinivasa Raghu, Abdelshakor, Mahmoud, Ali, Sara, Sebastian, Honeymol, Tariq, Mishal, Lal, Kumar, Abdelrahman, Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410437/
https://www.ncbi.nlm.nih.gov/pubmed/36013335
http://dx.doi.org/10.3390/life12081157
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author Hafez, Wael
Ahmed, Shougyat
Abbas, Nihad
Ahmed, Kamran
Kamran, Samera
Arya, Arun
Rao, Srinivasa Raghu
Abdelshakor, Mahmoud
Ali, Sara
Sebastian, Honeymol
Tariq, Mishal
Lal, Kumar
Abdelrahman, Ahmed
author_facet Hafez, Wael
Ahmed, Shougyat
Abbas, Nihad
Ahmed, Kamran
Kamran, Samera
Arya, Arun
Rao, Srinivasa Raghu
Abdelshakor, Mahmoud
Ali, Sara
Sebastian, Honeymol
Tariq, Mishal
Lal, Kumar
Abdelrahman, Ahmed
author_sort Hafez, Wael
collection PubMed
description (1) Background: The association between ABO blood groups and COVID-19 outcomes was investigated in several studies. The results were controversial. This study aimed to explore the association between ABO blood groups and COVID-19 outcomes. (2) Methods: This retrospective study included 303 COVID-19 patients treated at the NMC Royal Hospital in the United Arab Emirates between 8 April 2020 and 30 June 2020. (3) Results: The mean age of patients included in the study was 39.3 ± 10.7 years, and 72.9% of patients were males. The prevalence of blood groups O, A, B, and AB was 40.3%, 27.7%, 25.1%, and 6.9%, respectively. The correlation between ABO blood groups and COVID-19 outcomes was insignificant except in the AB group, with significantly higher odds of disease severity. Increased age, higher body mass index (BMI), and being of male gender increased the risk for pneumonia among all blood groups. Both increased age and higher BMI increased the risk of mortality, and increased age increased the risk of disease severity. Troponin and platelet counts were significantly different in the A group compared to the non-A groups. Time to viral clearance was not different among blood groups. However, adjustment for Rh groups resulted in a significantly shorter time in the B group. (4) Conclusions: There was no significant association between ABO blood groups and COVID-19 outcomes, with the exception of group AB.
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spelling pubmed-94104372022-08-26 ABO Blood Group in Relation to COVID-19 Susceptibility and Clinical Outcomes: A Retrospective Observational Study in the United Arab Emirates Hafez, Wael Ahmed, Shougyat Abbas, Nihad Ahmed, Kamran Kamran, Samera Arya, Arun Rao, Srinivasa Raghu Abdelshakor, Mahmoud Ali, Sara Sebastian, Honeymol Tariq, Mishal Lal, Kumar Abdelrahman, Ahmed Life (Basel) Article (1) Background: The association between ABO blood groups and COVID-19 outcomes was investigated in several studies. The results were controversial. This study aimed to explore the association between ABO blood groups and COVID-19 outcomes. (2) Methods: This retrospective study included 303 COVID-19 patients treated at the NMC Royal Hospital in the United Arab Emirates between 8 April 2020 and 30 June 2020. (3) Results: The mean age of patients included in the study was 39.3 ± 10.7 years, and 72.9% of patients were males. The prevalence of blood groups O, A, B, and AB was 40.3%, 27.7%, 25.1%, and 6.9%, respectively. The correlation between ABO blood groups and COVID-19 outcomes was insignificant except in the AB group, with significantly higher odds of disease severity. Increased age, higher body mass index (BMI), and being of male gender increased the risk for pneumonia among all blood groups. Both increased age and higher BMI increased the risk of mortality, and increased age increased the risk of disease severity. Troponin and platelet counts were significantly different in the A group compared to the non-A groups. Time to viral clearance was not different among blood groups. However, adjustment for Rh groups resulted in a significantly shorter time in the B group. (4) Conclusions: There was no significant association between ABO blood groups and COVID-19 outcomes, with the exception of group AB. MDPI 2022-07-29 /pmc/articles/PMC9410437/ /pubmed/36013335 http://dx.doi.org/10.3390/life12081157 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Hafez, Wael
Ahmed, Shougyat
Abbas, Nihad
Ahmed, Kamran
Kamran, Samera
Arya, Arun
Rao, Srinivasa Raghu
Abdelshakor, Mahmoud
Ali, Sara
Sebastian, Honeymol
Tariq, Mishal
Lal, Kumar
Abdelrahman, Ahmed
ABO Blood Group in Relation to COVID-19 Susceptibility and Clinical Outcomes: A Retrospective Observational Study in the United Arab Emirates
title ABO Blood Group in Relation to COVID-19 Susceptibility and Clinical Outcomes: A Retrospective Observational Study in the United Arab Emirates
title_full ABO Blood Group in Relation to COVID-19 Susceptibility and Clinical Outcomes: A Retrospective Observational Study in the United Arab Emirates
title_fullStr ABO Blood Group in Relation to COVID-19 Susceptibility and Clinical Outcomes: A Retrospective Observational Study in the United Arab Emirates
title_full_unstemmed ABO Blood Group in Relation to COVID-19 Susceptibility and Clinical Outcomes: A Retrospective Observational Study in the United Arab Emirates
title_short ABO Blood Group in Relation to COVID-19 Susceptibility and Clinical Outcomes: A Retrospective Observational Study in the United Arab Emirates
title_sort abo blood group in relation to covid-19 susceptibility and clinical outcomes: a retrospective observational study in the united arab emirates
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410437/
https://www.ncbi.nlm.nih.gov/pubmed/36013335
http://dx.doi.org/10.3390/life12081157
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