Cargando…

Evolution of β-lactamase-mediated cefiderocol resistance

BACKGROUND: Cefiderocol is a novel siderophore β-lactam with improved hydrolytic stability toward β-lactamases, including carbapenemases, achieved by combining structural moieties of two clinically efficient cephalosporins, ceftazidime and cefepime. Consequently, cefiderocol represents a treatment a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fröhlich, Christopher, Sørum, Vidar, Tokuriki, Nobuhiko, Johnsen, Pål Jarle, Samuelsen, Ørjan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410664/ https://www.ncbi.nlm.nih.gov/pubmed/35815680 http://dx.doi.org/10.1093/jac/dkac221

Ejemplares similares

OXA-48-Mediated Ceftazidime-Avibactam Resistance Is Associated with Evolutionary Trade-Offs
por: Fröhlich, Christopher, et al.
Publicado: (2019)

Cryptic β-Lactamase Evolution Is Driven by Low β-Lactam Concentrations
por: Fröhlich, Christopher, et al.
Publicado: (2021)

Evolutionary Instability of Collateral Susceptibility Networks in Ciprofloxacin-Resistant Clinical Escherichia coli Strains
por: Sørum, Vidar, et al.
Publicado: (2022)

In vitro activity of cefiderocol against Pseudomonas aeruginosa demonstrating evolved resistance to novel β-lactam/β-lactamase inhibitors
por: Shields, Ryan K, et al.
Publicado: (2023)

Resistance to Cefiderocol Involved Expression of PER-1 β-Lactamase and Downregulation of Iron Transporter System in Carbapenem-Resistant Acinetobacter baumannii
por: He, Yukun, et al.
Publicado: (2022)

Conserved collateral antibiotic susceptibility networks in diverse clinical strains of Escherichia coli
por: Podnecky, Nicole L., et al.
Publicado: (2018)

Structural and biochemical characterization of the environmental MBLs MYO-1, ECV-1 and SHD-1
por: Fröhlich, Christopher, et al.
Publicado: (2020)

Comprehensive exploration of the translocation, stability and substrate recognition requirements in VIM-2 lactamase
por: Chen, John Z, et al.
Publicado: (2020)

New Delhi Metallo-Beta-Lactamase Facilitates the Emergence of Cefiderocol Resistance in Enterobacter cloacae
por: Nurjadi, Dennis, et al.
Publicado: (2022)

ZN148 Is a Modular Synthetic Metallo-β-Lactamase Inhibitor That Reverses Carbapenem Resistance in Gram-Negative Pathogens In Vivo
por: Samuelsen, Ørjan, et al.
Publicado: (2020)

In Vitro Activities and Inoculum Effects of Cefiderocol and Aztreonam-Avibactam against Metallo-β-Lactamase-Producing Enterobacteriaceae
por: Huang, Yu-Shan, et al.
Publicado: (2023)

Stability and low induction propensity of cefiderocol against chromosomal AmpC β-lactamases of Pseudomonas aeruginosa and Enterobacter cloacae
por: Ito, Akinobu, et al.
Publicado: (2018)

Piggybacking on Niche Adaptation Improves the Maintenance of Multidrug‐Resistance Plasmids
por: Kloos, Julia, et al.
Publicado: (2021)

Evolution of cefiderocol resistance in Stenotrophomonas maltophilia using in vitro serial passage techniques
por: Werth, Brian J., et al.
Publicado: (2022)

The Effect of β-Lactam Antibiotics on the Evolution of Ceftazidime/Avibactam and Cefiderocol Resistance in KPC-Producing Klebsiella pneumoniae
por: Zhang, Ping, et al.
Publicado: (2023)

Stability and low induction propensity of cefiderocol against chromosomal AmpC β-lactamases of Pseudomonas aeruginosa and Enterobacter cloacae
por: Ito, Akinobu, et al.
Publicado: (2019)

Cefiderocol Resistance in Klebsiella pneumoniae Is Linked to SHV Extended-Spectrum β-Lactamase Activities and Functional Loss of the Outer Membrane Porin OmpK35
por: Moon, Sun Hee, et al.
Publicado: (2023)

Host dependent maintenance of a bla(NDM-1)-encoding plasmid in clinical Escherichia coli isolates
por: Gama, João Alves, et al.
Publicado: (2020)

Bloodstream Infection Due to a VIM-Metallo-β-Lactamase-Producing Klebsiella pneumoniae Treated with Cefiderocol in a Preterm Newborn
por: Monari, Caterina, et al.
Publicado: (2022)

1351. In vitro Activity of Cefiderocol (S-649266), a Siderophore Cephalosporin, Against Enterobacteriaceae With Defined Extended-Spectrum Β-Lactamases and Carbapenemases
por: Jacobs, Michael R, et al.
Publicado: (2018)

Cefiderocol
por: Soriano, María Cruz, et al.
Publicado: (2022)

Pharmacokinetics and Pharmacodynamics of Fosfomycin and Its Activity against Extended-Spectrum-β-Lactamase-, Plasmid-Mediated AmpC-, and Carbapenemase-Producing Escherichia coli in a Murine Urinary Tract Infection Model
por: Zykov, Ilya Nikolaevich, et al.
Publicado: (2018)

1297. In-Vitro Antibacterial Activities of Cefiderocol (S-649266) Alone and With the Addition of Beta-Lactamase Inhibitors Against Multidrug-resistant Acinetobacter baumannii
por: Abdul-Mutakabbir, Jacinda C, et al.
Publicado: (2020)

In Vitro Activity of Cefiderocol on Multiresistant Bacterial Strains and Genomic Analysis of Two Cefiderocol Resistant Strains
por: Padovani, Michela, et al.
Publicado: (2023)

Progressive in vivo development of resistance to cefiderocol in Pseudomonas aeruginosa
por: Sadek, Mustafa, et al.
Publicado: (2022)

Rapid detection of cefiderocol susceptibility/resistance in Acinetobacter baumannii
por: Raro, Otávio Hallal Ferreira, et al.
Publicado: (2023)

Change in the Antimicrobial Resistance Profile of Extended-Spectrum β-Lactamase-Producing Escherichia coli
por: Miyazaki, Motoyasu, et al.
Publicado: (2019)

2134. Impact of ADC ß-lactamase amino acid variation on cefiderocol (FDC) susceptibility in carbapenem-resistant Acinetobacter baumannii (CRAb) strains
por: Iovleva, Alina, et al.
Publicado: (2023)

Horizontal Plasmid Transfer among Klebsiella pneumoniae Isolates Is the Key Factor for Dissemination of Extended-Spectrum β-Lactamases among Children in Tanzania
por: Pedersen, Torunn, et al.
Publicado: (2020)

Exploring Cefiderocol Resistance Mechanisms in Burkholderia pseudomallei
por: Hall, Carina M., et al.
Publicado: (2023)

Fitness costs of various mobile genetic elements in Enterococcus faecium and Enterococcus faecalis
por: Starikova, Irina, et al.
Publicado: (2013)

Microbiological, Clinical, and PK/PD Features of the New Anti-Gram-Negative Antibiotics: β-Lactam/β-Lactamase Inhibitors in Combination and Cefiderocol—An All-Inclusive Guide for Clinicians
por: Principe, Luigi, et al.
Publicado: (2022)

Expanded-spectrum β-Lactamase and Plasmid-mediated Quinolone Resistance
por: Poirel, Laurent, et al.
Publicado: (2007)

Rationale and evidence for the use of new beta-lactam/beta-lactamase inhibitor combinations and cefiderocol in critically ill patients
por: Barbier, François, et al.
Publicado: (2023)

1452. Molecular Profile of β-Lactamase Genes and Siderophore-Dependent Iron Transporter Genes of Cefiderocol High MIC Isolates from SIDERO-WT Studies
por: Yamano, Yoshinori, et al.
Publicado: (2020)

In Vitro Activity of Cefiderocol Against Meropenem-Nonsusceptible Gram-Negative Bacilli with Defined β-Lactamase Carriage: SIDERO-WT Surveillance Studies, 2014–2019
por: Wise, Mark G., et al.
Publicado: (2023)

Collateral sensitivity constrains resistance evolution of the CTX-M-15 β-lactamase
por: Rosenkilde, Carola E. H., et al.
Publicado: (2019)

The Interplay of Electrostatics and Chemical Positioning in the Evolution of Antibiotic Resistance in TEM β-Lactamases
por: Schneider, Samuel H., et al.
Publicado: (2021)

No effect of natural transformation on the evolution of resistance to bacteriophages in the Acinetobacter baylyi model system
por: McLeman, Amy, et al.
Publicado: (2016)

Testing for the fitness benefits of natural transformation during community-embedded evolution
por: Winter, Macaulay, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_d23bg746e60j22ktk760g7gdlc