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Evolution of β-lactamase-mediated cefiderocol resistance

BACKGROUND: Cefiderocol is a novel siderophore β-lactam with improved hydrolytic stability toward β-lactamases, including carbapenemases, achieved by combining structural moieties of two clinically efficient cephalosporins, ceftazidime and cefepime. Consequently, cefiderocol represents a treatment a...

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Detalles Bibliográficos
Autores principales:	Fröhlich, Christopher, Sørum, Vidar, Tokuriki, Nobuhiko, Johnsen, Pål Jarle, Samuelsen, Ørjan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410664/ https://www.ncbi.nlm.nih.gov/pubmed/35815680 http://dx.doi.org/10.1093/jac/dkac221

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