Novel small molecules that increase the susceptibility of Neisseria gonorrhoeae to cationic antimicrobial peptides by inhibiting lipid A phosphoethanolamine transferase

OBJECTIVES: Neisseria gonorrhoeae is an exclusively human pathogen that commonly infects the urogenital tract resulting in gonorrhoea. Empirical treatment of gonorrhoea with antibiotics has led to multidrug resistance and the need for new therapeutics. Inactivation of lipooligosaccharide phosphoetha...

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Detalles Bibliográficos
Autores principales: Mullally, Christopher, Stubbs, Keith A, Thai, Van C, Anandan, Anandhi, Bartley, Stephanie, Scanlon, Martin J, Jarvis, Gary A, John, Constance M, Lim, Katherine Y L, Sullivan, Courtney M, Sarkar-Tyson, Mitali, Vrielink, Alice, Kahler, Charlene M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410672/
https://www.ncbi.nlm.nih.gov/pubmed/35770844
http://dx.doi.org/10.1093/jac/dkac204

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