Cargando…

Safety analysis of natural orifice specimen extraction surgery for colorectal cancer

This study investigated the safety, feasibility, and clinical outcomes of natural orifice specimen extraction surgery (NOSES) by collecting clinical from patients who underwent complete laparoscopic radical resection for colorectal cancer versus those who underwent conventional laparoscopic radical...

Descripción completa

Detalles Bibliográficos
Autores principales: Zheng, Shuai, Zhao, Zimin, Zheng, Honghong, Li, Jianjun, Yang, Ji, Zhao, Enhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410675/
https://www.ncbi.nlm.nih.gov/pubmed/36042685
http://dx.doi.org/10.1097/MD.0000000000030087
_version_ 1784775149805895680
author Zheng, Shuai
Zhao, Zimin
Zheng, Honghong
Li, Jianjun
Yang, Ji
Zhao, Enhong
author_facet Zheng, Shuai
Zhao, Zimin
Zheng, Honghong
Li, Jianjun
Yang, Ji
Zhao, Enhong
author_sort Zheng, Shuai
collection PubMed
description This study investigated the safety, feasibility, and clinical outcomes of natural orifice specimen extraction surgery (NOSES) by collecting clinical from patients who underwent complete laparoscopic radical resection for colorectal cancer versus those who underwent conventional laparoscopic radical resection for colorectal cancer. Patients with colorectal cancer were selected as the study sample and grouped according to the different surgical methods. A total of 182 patients were eligible for enrollment in the study, including 92 patients who underwent NOSES (NOSES group) and 90 patients who underwent conventional laparoscopic radical colorectal cancer surgery. In the NOSES group, a total of 14 cases were observed to have a postoperative abdominal infection, and the remaining 78 cases did not have an abdominal infection, which we refer to as the infected and uninfected groups in this paper for further analysis. There was no difference in surgical outcome between NOSES surgery and conventional laparoscopic surgery. Diabetes mellitus, prolonged drain retention, and prolonged operative time were risk factors for the development of abdominal infection in NOSES. In contrast, intraoperative use of specimen retrieval bags, use of transanal endoscopic operations, and intraoperative flushing of the abdominal cavity with dilute iodophenol were protective factors for the development of postoperative abdominal infections. NOSES for colorectal cancer is worth promoting because of its small trauma and quick postoperative recovery.
format Online
Article
Text
id pubmed-9410675
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Lippincott Williams & Wilkins
record_format MEDLINE/PubMed
spelling pubmed-94106752022-08-26 Safety analysis of natural orifice specimen extraction surgery for colorectal cancer Zheng, Shuai Zhao, Zimin Zheng, Honghong Li, Jianjun Yang, Ji Zhao, Enhong Medicine (Baltimore) Research Article This study investigated the safety, feasibility, and clinical outcomes of natural orifice specimen extraction surgery (NOSES) by collecting clinical from patients who underwent complete laparoscopic radical resection for colorectal cancer versus those who underwent conventional laparoscopic radical resection for colorectal cancer. Patients with colorectal cancer were selected as the study sample and grouped according to the different surgical methods. A total of 182 patients were eligible for enrollment in the study, including 92 patients who underwent NOSES (NOSES group) and 90 patients who underwent conventional laparoscopic radical colorectal cancer surgery. In the NOSES group, a total of 14 cases were observed to have a postoperative abdominal infection, and the remaining 78 cases did not have an abdominal infection, which we refer to as the infected and uninfected groups in this paper for further analysis. There was no difference in surgical outcome between NOSES surgery and conventional laparoscopic surgery. Diabetes mellitus, prolonged drain retention, and prolonged operative time were risk factors for the development of abdominal infection in NOSES. In contrast, intraoperative use of specimen retrieval bags, use of transanal endoscopic operations, and intraoperative flushing of the abdominal cavity with dilute iodophenol were protective factors for the development of postoperative abdominal infections. NOSES for colorectal cancer is worth promoting because of its small trauma and quick postoperative recovery. Lippincott Williams & Wilkins 2022-08-26 /pmc/articles/PMC9410675/ /pubmed/36042685 http://dx.doi.org/10.1097/MD.0000000000030087 Text en Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC) (https://creativecommons.org/licenses/by-nc/4.0/) , where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal.
spellingShingle Research Article
Zheng, Shuai
Zhao, Zimin
Zheng, Honghong
Li, Jianjun
Yang, Ji
Zhao, Enhong
Safety analysis of natural orifice specimen extraction surgery for colorectal cancer
title Safety analysis of natural orifice specimen extraction surgery for colorectal cancer
title_full Safety analysis of natural orifice specimen extraction surgery for colorectal cancer
title_fullStr Safety analysis of natural orifice specimen extraction surgery for colorectal cancer
title_full_unstemmed Safety analysis of natural orifice specimen extraction surgery for colorectal cancer
title_short Safety analysis of natural orifice specimen extraction surgery for colorectal cancer
title_sort safety analysis of natural orifice specimen extraction surgery for colorectal cancer
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410675/
https://www.ncbi.nlm.nih.gov/pubmed/36042685
http://dx.doi.org/10.1097/MD.0000000000030087
work_keys_str_mv AT zhengshuai safetyanalysisofnaturalorificespecimenextractionsurgeryforcolorectalcancer
AT zhaozimin safetyanalysisofnaturalorificespecimenextractionsurgeryforcolorectalcancer
AT zhenghonghong safetyanalysisofnaturalorificespecimenextractionsurgeryforcolorectalcancer
AT lijianjun safetyanalysisofnaturalorificespecimenextractionsurgeryforcolorectalcancer
AT yangji safetyanalysisofnaturalorificespecimenextractionsurgeryforcolorectalcancer
AT zhaoenhong safetyanalysisofnaturalorificespecimenextractionsurgeryforcolorectalcancer