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Diagnosis stability and outcome of psychotic episodes in a Romanian group of children and adolescents

Studies on early onset schizophrenia are limited because of their low prevalence but the reported results stated that early onset is associated with a poorer outcome. The present research analyzed the stability rate of the psychotic-related disorders from childhood to adult life. The study was based...

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Autores principales: Rad, Florina, Stancu, Mihaela, Andrei, Lucia-Emanuela, Linca, Florentina-Ionela, Mariana Buică, Alexandra, Leti, Maria-Madalina, Dobrescu, Iuliana, Mihailescu, Ilinca, Efrim-Budisteanu, Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410679/
https://www.ncbi.nlm.nih.gov/pubmed/36042658
http://dx.doi.org/10.1097/MD.0000000000030288
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author Rad, Florina
Stancu, Mihaela
Andrei, Lucia-Emanuela
Linca, Florentina-Ionela
Mariana Buică, Alexandra
Leti, Maria-Madalina
Dobrescu, Iuliana
Mihailescu, Ilinca
Efrim-Budisteanu, Magdalena
author_facet Rad, Florina
Stancu, Mihaela
Andrei, Lucia-Emanuela
Linca, Florentina-Ionela
Mariana Buică, Alexandra
Leti, Maria-Madalina
Dobrescu, Iuliana
Mihailescu, Ilinca
Efrim-Budisteanu, Magdalena
author_sort Rad, Florina
collection PubMed
description Studies on early onset schizophrenia are limited because of their low prevalence but the reported results stated that early onset is associated with a poorer outcome. The present research analyzed the stability rate of the psychotic-related disorders from childhood to adult life. The study was based on an observational, retrospective, descriptive analysis study. The subjects were selected from patients admitted to the pediatric psychiatry ward of “Alexandru Obregia” Psychiatry Hospital between 2009 and 2018 for a psychosis-related disorder, who were 18 years or older at the moment of data collection and who also had admissions into the adult’s psychiatry wards of the hospital. Of the 115 subjects, 93, representing 80.87% of the total, maintained a diagnosis of psychotic spectrum disorder into adulthood. The diagnosis was maintained in 82.4% of cases with onset before 13 years old and 80.6% of cases with onset after the age of 13 years of age. Of the 42 subjects who presented affective symptoms during childhood, 71.43% also presented affective symptoms into adulthood. These findings indicate an important stability rate of psychosis from childhood and adulthood and come in accordance with the theory of overlap between psychotic and affective disorders. The results underline the importance of an accurate diagnosis of early and very early onset schizophrenia (VEOS), the need for early and multimodal intervention, but also the need for long-term management of these patients and continuing research regarding psychotic-related disorders in children and adolescents.
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spelling pubmed-94106792022-08-26 Diagnosis stability and outcome of psychotic episodes in a Romanian group of children and adolescents Rad, Florina Stancu, Mihaela Andrei, Lucia-Emanuela Linca, Florentina-Ionela Mariana Buică, Alexandra Leti, Maria-Madalina Dobrescu, Iuliana Mihailescu, Ilinca Efrim-Budisteanu, Magdalena Medicine (Baltimore) Research Article Studies on early onset schizophrenia are limited because of their low prevalence but the reported results stated that early onset is associated with a poorer outcome. The present research analyzed the stability rate of the psychotic-related disorders from childhood to adult life. The study was based on an observational, retrospective, descriptive analysis study. The subjects were selected from patients admitted to the pediatric psychiatry ward of “Alexandru Obregia” Psychiatry Hospital between 2009 and 2018 for a psychosis-related disorder, who were 18 years or older at the moment of data collection and who also had admissions into the adult’s psychiatry wards of the hospital. Of the 115 subjects, 93, representing 80.87% of the total, maintained a diagnosis of psychotic spectrum disorder into adulthood. The diagnosis was maintained in 82.4% of cases with onset before 13 years old and 80.6% of cases with onset after the age of 13 years of age. Of the 42 subjects who presented affective symptoms during childhood, 71.43% also presented affective symptoms into adulthood. These findings indicate an important stability rate of psychosis from childhood and adulthood and come in accordance with the theory of overlap between psychotic and affective disorders. The results underline the importance of an accurate diagnosis of early and very early onset schizophrenia (VEOS), the need for early and multimodal intervention, but also the need for long-term management of these patients and continuing research regarding psychotic-related disorders in children and adolescents. Lippincott Williams & Wilkins 2022-08-26 /pmc/articles/PMC9410679/ /pubmed/36042658 http://dx.doi.org/10.1097/MD.0000000000030288 Text en Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY) (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Rad, Florina
Stancu, Mihaela
Andrei, Lucia-Emanuela
Linca, Florentina-Ionela
Mariana Buică, Alexandra
Leti, Maria-Madalina
Dobrescu, Iuliana
Mihailescu, Ilinca
Efrim-Budisteanu, Magdalena
Diagnosis stability and outcome of psychotic episodes in a Romanian group of children and adolescents
title Diagnosis stability and outcome of psychotic episodes in a Romanian group of children and adolescents
title_full Diagnosis stability and outcome of psychotic episodes in a Romanian group of children and adolescents
title_fullStr Diagnosis stability and outcome of psychotic episodes in a Romanian group of children and adolescents
title_full_unstemmed Diagnosis stability and outcome of psychotic episodes in a Romanian group of children and adolescents
title_short Diagnosis stability and outcome of psychotic episodes in a Romanian group of children and adolescents
title_sort diagnosis stability and outcome of psychotic episodes in a romanian group of children and adolescents
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410679/
https://www.ncbi.nlm.nih.gov/pubmed/36042658
http://dx.doi.org/10.1097/MD.0000000000030288
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