ROCK inhibition with Y-27632 reduces joint inflammation and damage in serum-induced arthritis model and decreases in vitro osteoclastogenesis in patients with early arthritis

Rheumatoid arthritis (RA) is a common chronic inflammatory disease affecting primarily peripheral joints, which is only partially controlled with current treatments. RA leads to pain, disability, deformities, and life expectancy shortening. Its pathogenesis is complex involving multiple cell types a...

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Detalles Bibliográficos
Autores principales: Rodríguez-Trillo, Angela, Pena, Carmen, García, Samuel, Pérez-Pampín, Eva, Rodríguez-López, Marina, Mera-Varela, Antonio, González, Antonio, Conde, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410766/
https://www.ncbi.nlm.nih.gov/pubmed/36032152
http://dx.doi.org/10.3389/fimmu.2022.858069

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410766/
https://www.ncbi.nlm.nih.gov/pubmed/36032152
http://dx.doi.org/10.3389/fimmu.2022.858069

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