Cargando…

Molecular basis of anti-CRISPR operon repression by Aca10

CRISPR-Cas systems are bacterial defense systems for fighting against invaders such as bacteriophages and mobile genetic elements. To escape destruction by these bacterial immune systems, phages have co-evolved multiple anti-CRISPR (Acr) proteins, which inhibit CRISPR-Cas function. Many acr genes fo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, So Yeon, Birkholz, Nils, Fineran, Peter C, Park, Hyun Ho
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410881/ https://www.ncbi.nlm.nih.gov/pubmed/35920325 http://dx.doi.org/10.1093/nar/gkac656

Ejemplares similares

Molecular basis of dual anti-CRISPR and auto-regulatory functions of AcrIF24
por: Kim, Gi Eob, et al.
Publicado: (2022)

Crystal structure of the anti-CRISPR repressor Aca2
por: Usher, Ben, et al.
Publicado: (2021)

The autoregulator Aca2 mediates anti-CRISPR repression
por: Birkholz, Nils, et al.
Publicado: (2019)

Structural basis for anti-CRISPR repression mediated by bacterial operon proteins Aca1 and Aca2
por: Liu, Yanhong, et al.
Publicado: (2021)

Widespread repression of anti-CRISPR production by anti-CRISPR-associated proteins
por: Shehreen, Saadlee, et al.
Publicado: (2022)

Crystal structure of an anti-CRISPR protein, AcrIIA1
por: Ka, Donghyun, et al.
Publicado: (2018)

Inactivation of the dimeric Rap(pLS20) anti-repressor of the conjugation operon is mediated by peptide-induced tetramerization
por: Crespo, Isidro, et al.
Publicado: (2020)

Molecular basis of stepwise cyclic tetra-adenylate cleavage by the type III CRISPR ring nuclease Crn1/Sso2081
por: Du, Liyang, et al.
Publicado: (2023)

Intrinsic disorder is essential for Cas9 inhibition of anti-CRISPR AcrIIA5
por: An, So Young, et al.
Publicado: (2020)

Structural basis for substrate recognition and cleavage by the dimerization-dependent CRISPR–Cas12f nuclease
por: Xiao, Renjian, et al.
Publicado: (2021)

Structural basis of cyclic oligoadenylate degradation by ancillary Type III CRISPR-Cas ring nucleases
por: Molina, Rafael, et al.
Publicado: (2021)

Molecular basis of cobalamin-dependent RNA modification
por: Dowling, Daniel P., et al.
Publicado: (2016)

Novel anti-repression mechanism of H-NS proteins by a phage protein
por: Bdira, Fredj Ben, et al.
Publicado: (2021)

Anti-prion activity of an RNA aptamer and its structural basis
por: Mashima, Tsukasa, et al.
Publicado: (2013)

Structural basis for inhibition of the type I-F CRISPR–Cas surveillance complex by AcrIF4, AcrIF7 and AcrIF14
por: Gabel, Clinton, et al.
Publicado: (2020)

Conformational and thermodynamic hallmarks of DNA operator site specificity in the copper sensitive operon repressor from Streptomyces lividans
por: Tan, Benedict G., et al.
Publicado: (2014)

Molecular basis for the lack of enantioselectivity of human 3-phosphoglycerate kinase
por: Gondeau, C., et al.
Publicado: (2008)

Structural basis of sequestration of the anti-Shine-Dalgarno sequence in the Bacteroidetes ribosome
por: Jha, Vikash, et al.
Publicado: (2020)

Structural and mechanistic insights into the CRISPR inhibition of AcrIF7
por: Kim, Iktae, et al.
Publicado: (2020)

Structural mechanism of transcription regulation of the Staphylococcus aureus multidrug efflux operon mepRA by the MarR family repressor MepR
por: Birukou, Ivan, et al.
Publicado: (2014)

Toxin–antitoxin operon kacAT of Klebsiella pneumoniae is regulated by conditional cooperativity via a W-shaped KacA–KacT complex
por: Qian, Hongliang, et al.
Publicado: (2019)

Molecular basis of Diamond–Blackfan anemia: structure and function analysis of RPS19
por: Gregory, Lynn A., et al.
Publicado: (2007)

Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus
por: Muñoz, Inés G., et al.
Publicado: (2011)

Structural basis for the molecular recognition of polyadenosine RNA by Nab2 Zn fingers
por: Kuhlmann, Sonja I., et al.
Publicado: (2014)

Molecular basis for the substrate specificity and catalytic mechanism of thymine-7-hydroxylase in fungi
por: Li, Wenjing, et al.
Publicado: (2015)

Structural basis for the dynamics of human methionyl-tRNA synthetase in multi-tRNA synthetase complexes
por: Kim, Dong Kyu, et al.
Publicado: (2021)

Molecular basis for the wide range of affinity found in Csr/Rsm protein–RNA recognition
por: Duss, Olivier, et al.
Publicado: (2014)

Molecular basis for bipartite recognition of histone H3 by the PZP domain of PHF14
por: Zheng, Shuangping, et al.
Publicado: (2021)

AcaFinder: Genome Mining for Anti-CRISPR-Associated Genes
por: Yang, Bowen, et al.
Publicado: (2022)

The Ighmbp2 helicase structure reveals the molecular basis for disease-causing mutations in DMSA1
por: Lim, Siew Choo, et al.
Publicado: (2012)

Molecular basis for cell-wall recycling regulation by transcriptional repressor MurR in Escherichia coli
por: Zhang, Ya, et al.
Publicado: (2022)

Structural basis of flagellar motility regulation by the MogR repressor and the GmaR antirepressor in Listeria monocytogenes
por: Cho, So Yeon, et al.
Publicado: (2022)

Molecular architecture of human polycomb repressive complex 2
por: Ciferri, Claudio, et al.
Publicado: (2012)

Structural basis of the fanconi anemia-associated mutations within the FANCA and FANCG complex
por: Jeong, Eunyoung, et al.
Publicado: (2020)

Structural basis of σ appropriation
por: Shi, Jing, et al.
Publicado: (2019)

Molecular basis for asymmetry sensing of siRNAs by the Drosophila Loqs-PD/Dcr-2 complex in RNA interference
por: Tants, Jan-Niklas, et al.
Publicado: (2017)

Molecular basis of abasic site sensing in single-stranded DNA by the SRAP domain of E. coli yedK
por: Wang, Na, et al.
Publicado: (2019)

Molecular organization of the type II-A CRISPR adaptation module and its interaction with Cas9 via Csn2
por: Ka, Donghyun, et al.
Publicado: (2018)

Antitoxin autoregulation of M. tuberculosis toxin-antitoxin expression through negative cooperativity arising from multiple inverted repeat sequences
por: Beck, Izaak N., et al.
Publicado: (2020)

Structures of mammalian GLD-2 proteins reveal molecular basis of their functional diversity in mRNA and microRNA processing
por: Ma, Xiao-Yan, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_ut9jk844bsudfiemk1bugphlum