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Structural assembly of the nucleic-acid-binding Thp3–Csn12–Sem1 complex functioning in mRNA splicing

PCI domain proteins play important roles in post-transcriptional gene regulation. In the TREX-2 complex, PCI domain-containing Sac3 and Thp1 proteins and accessory Sem1 protein form a ternary complex required for mRNA nuclear export. In contrast, structurally related Thp3–Csn12–Sem1 complex mediates...

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Detalles Bibliográficos
Autores principales:	Kuang, Zhiling, Ke, Jiyuan, Hong, Jiong, Zhu, Zhongliang, Niu, Liwen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410885/ https://www.ncbi.nlm.nih.gov/pubmed/35904806 http://dx.doi.org/10.1093/nar/gkac634

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