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A phage parasite deploys a nicking nuclease effector to inhibit viral host replication

PLEs (phage-inducible chromosomal island-like elements) are phage parasites integrated into the chromosome of epidemic Vibrio cholerae. In response to infection by its viral host ICP1, PLE excises, replicates and hijacks ICP1 structural components for transduction. Through an unknown mechanism, PLE...

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Detalles Bibliográficos
Autores principales:	LeGault, Kristen N, Barth, Zachary K, DePaola, Peter, Seed, Kimberley D
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	NAR Breakthrough Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410903/ https://www.ncbi.nlm.nih.gov/pubmed/35066583 http://dx.doi.org/10.1093/nar/gkac002

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