Strand switching mechanism of Pif1 helicase induced by its collision with a G-quadruplex embedded in dsDNA

G-rich sequences found at multiple sites throughout all genomes may form secondary structures called G-quadruplexes (G4), which act as roadblocks for molecular motors. Among the enzymes thought to process these structures, the Pif1 DNA helicase is considered as an archetypical G4-resolvase and its a...

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Detalles Bibliográficos
Autores principales: Valle-Orero, Jessica, Rieu, Martin, Tran, Phong Lan Thao, Joubert, Alexandra, Raj, Saurabh, Allemand, Jean-François, Croquette, Vincent, Boulé, Jean-Baptiste
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410907/
https://www.ncbi.nlm.nih.gov/pubmed/35947696
http://dx.doi.org/10.1093/nar/gkac667

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9410907/
https://www.ncbi.nlm.nih.gov/pubmed/35947696
http://dx.doi.org/10.1093/nar/gkac667

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