A novel decellularized matrix of Wnt signaling-activated osteocytes accelerates the repair of critical-sized parietal bone defects with osteoclastogenesis, angiogenesis, and neurogenesis

Cell source is the key to decellularized matrix (DM) strategy. This study compared 3 cell types, osteocytes with/without dominant active Wnt/β-catenin signaling (daCO and WTO) and bone marrow stromal cells (BMSCs) for their DMs in bone repair. Decellularization removes all organelles and >95% DNA...

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Detalles Bibliográficos
Autores principales: Wang, Xiaofang, Ma, Yufei, Chen, Jie, Liu, Yujiao, Liu, Guangliang, Wang, Pengtao, Wang, Bo, Taketo, Makoto M., Bellido, Teresita, Tu, Xiaolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9411072/
https://www.ncbi.nlm.nih.gov/pubmed/36093329
http://dx.doi.org/10.1016/j.bioactmat.2022.07.017

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