Recent studies on chemical constituents of Ophiorrhiza plants

Ophiorrhiza plants (Family Rubiaceae) are known to produce diverse monoterpenoid indole alkaloids including camptothecin with potent antitumor activity. This review contains a summary of recent chemical studies reported over the past 10 years regarding alkaloids (monoterpenoid indole and tetrahydroi...

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Autor principal: Kitajima, Mariko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9411090/
https://www.ncbi.nlm.nih.gov/pubmed/35902551
http://dx.doi.org/10.1007/s11418-022-01640-3
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author Kitajima, Mariko
author_facet Kitajima, Mariko
author_sort Kitajima, Mariko
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description Ophiorrhiza plants (Family Rubiaceae) are known to produce diverse monoterpenoid indole alkaloids including camptothecin with potent antitumor activity. This review contains a summary of recent chemical studies reported over the past 10 years regarding alkaloids (monoterpenoid indole and tetrahydroisoquinoline alkaloids, and cyclopeptide) in Ophiorrhiza plants. In addition, the alkaloid biosynthetic pathways based on their reported structures were proposed.
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spelling pubmed-94110902022-08-27 Recent studies on chemical constituents of Ophiorrhiza plants Kitajima, Mariko J Nat Med Review Ophiorrhiza plants (Family Rubiaceae) are known to produce diverse monoterpenoid indole alkaloids including camptothecin with potent antitumor activity. This review contains a summary of recent chemical studies reported over the past 10 years regarding alkaloids (monoterpenoid indole and tetrahydroisoquinoline alkaloids, and cyclopeptide) in Ophiorrhiza plants. In addition, the alkaloid biosynthetic pathways based on their reported structures were proposed. Springer Nature Singapore 2022-07-28 2022 /pmc/articles/PMC9411090/ /pubmed/35902551 http://dx.doi.org/10.1007/s11418-022-01640-3 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Review
Kitajima, Mariko
Recent studies on chemical constituents of Ophiorrhiza plants
title Recent studies on chemical constituents of Ophiorrhiza plants
title_full Recent studies on chemical constituents of Ophiorrhiza plants
title_fullStr Recent studies on chemical constituents of Ophiorrhiza plants
title_full_unstemmed Recent studies on chemical constituents of Ophiorrhiza plants
title_short Recent studies on chemical constituents of Ophiorrhiza plants
title_sort recent studies on chemical constituents of ophiorrhiza plants
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9411090/
https://www.ncbi.nlm.nih.gov/pubmed/35902551
http://dx.doi.org/10.1007/s11418-022-01640-3
work_keys_str_mv AT kitajimamariko recentstudiesonchemicalconstituentsofophiorrhizaplants

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