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SARS-CoV-2 CD8(+) T cell killing assays using replicating viruses and transgenic antigens

The quality of an antigen-specific CD8(+) T cell repertoire is crucial for the clearance of intracellular pathogens, in particular for viral infections. Here, we describe killing assays to determine the function of CD8(+) T cells engineered with SARS-CoV-2-specific T cell receptors in a near-physiol...

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Detalles Bibliográficos
Autores principales:	Mateyka, Laura M., Grass, Vincent, Pichlmair, Andreas, Busch, Dirk H., D’Ippolito, Elvira
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9411149/ https://www.ncbi.nlm.nih.gov/pubmed/36152303 http://dx.doi.org/10.1016/j.xpro.2022.101699

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