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Oligodendrocyte differentiation alters tRNA modifications and codon optimality-mediated mRNA decay

Oligodendrocytes are specialized cells that confer neuronal myelination in the central nervous system. Leukodystrophies associated with oligodendrocyte deficits and hypomyelination are known to result when a number of tRNA metabolism genes are mutated. Thus, for unknown reasons, oligodendrocytes may...

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Detalles Bibliográficos
Autores principales:	Martin, Sophie, Allan, Kevin C., Pinkard, Otis, Sweet, Thomas, Tesar, Paul J., Coller, Jeff
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9411196/ https://www.ncbi.nlm.nih.gov/pubmed/36008413 http://dx.doi.org/10.1038/s41467-022-32766-3

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