Cargando…

CD47 interactions with exportin-1 limit the targeting of m(7)G-modified RNAs to extracellular vesicles

CD47 is a marker of self and a signaling receptor for thrombospondin-1 that is also a component of extracellular vesicles (EVs) released by various cell types. Previous studies identified CD47-dependent functional effects of T cell EVs on target cells, mediated by delivery of their RNA contents, and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kaur, Sukhbir, Saldana, Alejandra Cavazos, Elkahloun, Abdel G., Petersen, Jennifer D., Arakelyan, Anush, Singh, Satya P., Jenkins, Lisa M., Kuo, Bethany, Reginauld, Bianca, Jordan, David G., Tran, Andy D., Wu, Weiwei, Zimmerberg, Joshua, Margolis, Leonid, Roberts, David D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Netherlands 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9411329/ https://www.ncbi.nlm.nih.gov/pubmed/34841476 http://dx.doi.org/10.1007/s12079-021-00646-y

Ejemplares similares

CD63(+) and MHC Class I(+) Subsets of Extracellular Vesicles Produced by Wild-Type and CD47-Deficient Jurkat T Cells Have Divergent Functional Effects on Endothelial Cell Gene Expression
por: Kaur, Sukhbir, et al.
Publicado: (2021)

CD63, MHC class 1, and CD47 identify subsets of extracellular vesicles containing distinct populations of noncoding RNAs
por: Kaur, Sukhbir, et al.
Publicado: (2018)

CD47-dependent immunomodulatory and angiogenic activities of extracellular vesicles produced by T cells
por: Kaur, Sukhbir, et al.
Publicado: (2014)

Macrophage-derived HIV-1 carries bioactive TGF-beta
por: Arakelyan, Anush, et al.
Publicado: (2019)

A function-blocking CD47 antibody suppresses stem cell and EGF signaling in triple-negative breast cancer
por: Kaur, Sukhbir, et al.
Publicado: (2016)

Extracellular vesicles released from the filarial parasite Brugia malayi downregulate the host mTOR pathway
por: Ricciardi, Alessandra, et al.
Publicado: (2021)

Thrombospondin-1 Signaling through CD47 Inhibits Self-renewal by Regulating c-Myc and Other Stem Cell Transcription Factors
por: Kaur, Sukhbir, et al.
Publicado: (2013)

Extracellular Vesicles Carry HIV Env and Facilitate Hiv Infection of Human Lymphoid Tissue
por: Arakelyan, Anush, et al.
Publicado: (2017)

Syncytin 1 dependent horizontal transfer of marker genes from retrovirally transduced cells
por: Uygur, Berna, et al.
Publicado: (2019)

Identification of Schlafen-11 as a Target of CD47 Signaling That Regulates Sensitivity to Ionizing Radiation and Topoisomerase Inhibitors
por: Kaur, Sukhbir, et al.
Publicado: (2019)

Importins and exportins in cellular differentiation
por: Okada, Norihisa, et al.
Publicado: (2008)

Flow Virometry to Analyze Antigenic Spectra of Virions and Extracellular Vesicles
por: Arakelyan, Anush, et al.
Publicado: (2017)

Addition of thrombin reduces the recovery of extracellular vesicles from blood plasma
por: Arakelyan, Anush, et al.
Publicado: (2016)

Exportin 1 inhibition as antiviral therapy
por: Uddin, Md. Hafiz, et al.
Publicado: (2020)

Importins and Exportins Regulating Allergic Immune Responses
por: Aggarwal, Ankita, et al.
Publicado: (2014)

Therapeutic Targeting of Exportin-1 in Childhood Cancer
por: Galinski, Basia, et al.
Publicado: (2021)

Exportin-5 orthologues are functionally divergent among species
por: Shibata, Satoshi, et al.
Publicado: (2006)

Structural Basis of Targeting the Exportin CRM1 in Cancer
por: Dickmanns, Achim, et al.
Publicado: (2015)

The Role of Exportin-5 in MicroRNA Biogenesis and Cancer
por: Wu, Ke, et al.
Publicado: (2018)

Prognostic roles of the transcriptional expression of exportins in hepatocellular carcinoma
por: Chen, Lubiao, et al.
Publicado: (2019)

Exportin‐T promotes tumor proliferation and invasion in hepatocellular carcinoma
por: Lin, Jianwei, et al.
Publicado: (2018)

Exportin-inspired artificial cell nuclear-exporting nanosystems
por: Inui, Mitsuo, et al.
Publicado: (2022)

Differential regulation by CD47 and thrombospondin-1 of extramedullary erythropoiesis in mouse spleen
por: Banerjee, Rajdeep, et al.
Publicado: (2023)

Combined Targeting of Estrogen Receptor Alpha and Exportin 1 in Metastatic Breast Cancers
por: Cotul, Eylem Kulkoyluoglu, et al.
Publicado: (2020)

Exportin-5 mediates nuclear export of SRP RNA in vertebrates
por: Takeiwa, Toshihiko, et al.
Publicado: (2015)

HIV-1 Expressing the Envelopes of Transmitted/Founder or Control/Reference Viruses Have Similar Infection Patterns of CD4 T-Cells in Human Cervical Tissue Ex Vivo
por: Merbah, Melanie, et al.
Publicado: (2012)

Flow virometry analysis of envelope glycoprotein conformations on individual HIV virions
por: Arakelyan, Anush, et al.
Publicado: (2017)

Single vesicle analysis of CD47 association with integrins and tetraspanins on extracellular vesicles released by T lymphoblast and prostate carcinoma cells
por: Kaur, Sukhbir, et al.
Publicado: (2022)

CD47-Dependent Regulation of Immune Checkpoint Gene Expression and MYCN mRNA Splicing in Murine CD8 and Jurkat T Cells
por: Kaur, Sukhbir, et al.
Publicado: (2023)

Allosteric control of the exportin CRM1 unraveled by crystal structure analysis
por: Monecke, Thomas, et al.
Publicado: (2014)

Expression and function of exportin 6 in full-grown and growing porcine oocytes
por: ONUMA, Asuka, et al.
Publicado: (2019)

Exportin-T: A Novel Prognostic Predictor and Potential Therapeutic Target for Neuroblastoma
por: Pan, Li-Jia, et al.
Publicado: (2021)

An ARF6-Exportin-5 Axis Delivers pre-miRNA Cargo to Tumor Microvesicles.
por: Clancy, James W., et al.
Publicado: (2019)

Exportin Crm1 is important for Swi6 nuclear shuttling and MBF transcription activation in Saccharomyces cerevisiae
por: Belanger, Kenneth D., et al.
Publicado: (2022)

Human cytomegalovirus-infected cells release extracellular vesicles that carry viral surface proteins
por: Zicari, Sonia, et al.
Publicado: (2018)

Secreted Thrombospondin-1 Regulates Macrophage Interleukin-1β Production and Activation through CD47
por: Stein, Erica V., et al.
Publicado: (2016)

Inhibition of exportin-1 function results in rapid cell cycle-associated DNA damage in cancer cells
por: Burke, Russell T., et al.
Publicado: (2017)

In vitro toxicity and efficacy of verdinexor, an exportin 1 inhibitor, on opportunistic viruses affecting immunocompromised individuals
por: Widman, Douglas G., et al.
Publicado: (2018)

Binding of Carbonic Anhydrase IX to 45S rDNA Genes Is Prevented by Exportin-1 in Hypoxic Cells
por: Sasso, Emanuele, et al.
Publicado: (2015)

Loss of CD47 alters CD8+ T cell activation in vitro and immunodynamics in mice
por: Nath, Pulak R., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ucedql1p62j1cleuna3o6ggl0p