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Regulation of neuroendocrine plasticity by the RNA-binding protein ZFP36L1

Some small cell lung cancers (SCLCs) are highly sensitive to inhibitors of the histone demethylase LSD1. LSD1 inhibitors are thought to induce their anti-proliferative effects by blocking neuroendocrine differentiation, but the mechanisms by which LSD1 controls the SCLC neuroendocrine phenotype are...

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Detalles Bibliográficos
Autores principales:	Chen, Hsiao-Yun, Durmaz, Yavuz T., Li, Yixiang, Sabet, Amin H., Vajdi, Amir, Denize, Thomas, Walton, Emily, Laimon, Yasmin Nabil, Doench, John G., Mahadevan, Navin R., Losman, Julie-Aurore, Barbie, David A., Tolstorukov, Michael Y., Rudin, Charles M., Sen, Triparna, Signoretti, Sabina, Oser, Matthew G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9411550/ https://www.ncbi.nlm.nih.gov/pubmed/36008402 http://dx.doi.org/10.1038/s41467-022-31998-7

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