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Local anesthetic lidocaine-inducible gene, growth differentiation factor-15 suppresses the growth of cancer cell lines

Administration of local anesthetics, such as lidocaine, in the perioperative period improves outcomes of cancer patients. However, its precise mechanism is still unresolved. The growth of human cancer cell lines, including HeLa cells, are suppressed by lidocaine treatment. We identified that growth...

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Detalles Bibliográficos
Autores principales: Haraguchi-Suzuki, Keiko, Kawabata-Iwakawa, Reika, Suzuki, Toru, Suto, Takashi, Takazawa, Tomonori, Saito, Shigeru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9411556/
https://www.ncbi.nlm.nih.gov/pubmed/36008442
http://dx.doi.org/10.1038/s41598-022-18572-3