Broad clinical manifestations of polygenic risk for coronary artery disease in the Women’s Health Initiative

BACKGROUND: The genetic basis for coronary artery disease (CAD) risk is highly complex. Genome-wide polygenic risk scores (PRS) can help to quantify that risk, but the broader impacts of polygenic risk for CAD are not well characterized. METHODS: We measured polygenic risk for CAD using the meta gen...

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Detalles Bibliográficos
Autores principales: Clarke, Shoa L., Parham, Matthew, Lankester, Joanna, Shadyab, Aladdin H., Liu, Simin, Kooperberg, Charles, Manson, JoAnn E., Tcheandjieu, Catherine, Assimes, Themistocles L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9411562/
https://www.ncbi.nlm.nih.gov/pubmed/36034645
http://dx.doi.org/10.1038/s43856-022-00171-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9411562/
https://www.ncbi.nlm.nih.gov/pubmed/36034645
http://dx.doi.org/10.1038/s43856-022-00171-y

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