Zeb1 sustains hematopoietic stem cell functions by suppressing mitofusin-2-mediated mitochondrial fusion

Metabolic status is essential in maintaining normal functions of hematopoietic stem cells (HSCs). However, how the dynamic of the mitochondrion, as a central organelle in metabolism, is molecularly regulated to orchestrate metabolism and HSC stemness remains to be elucidated. Here, we focus on the r...

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Detalles Bibliográficos
Autores principales: Zhang, Kai, Zhao, Huifang, Sheng, Yaru, Chen, Xinyu, Xu, Penghui, Wang, Jinming, Ji, Zhongzhong, He, Yuman, Gao, Wei-Qiang, Zhu, Helen He
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9411618/
https://www.ncbi.nlm.nih.gov/pubmed/36008379
http://dx.doi.org/10.1038/s41419-022-05194-w

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