High incidence of minor and micro breakpoints in Chronic Myeloid Leukaemia with additional cytogenetic abnormalities at diagnosis – the Western Australian series

INTRODUCTION AND OBJECTIVE: Chronic Myeloid Leukaemia (CML) is defined by the presence of the Philadelphia chromosome, a balanced translocation between chromosomes 9 and 22 that results in the constitutively active tyrosine kinase, BCR-ABL1. Additional chromosomal abnormalities (ACAs) at diagnosis o...

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Detalles Bibliográficos
Autores principales: Leung, Emily, de Kraa, Rebecca, Louw, Alison, Cooney, Julian P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9411674/
https://www.ncbi.nlm.nih.gov/pubmed/36032422
http://dx.doi.org/10.1016/j.lrr.2022.100344

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