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Nicotinamide riboside alleviates exercise intolerance in ANT1-deficient mice

OBJECTIVE: Mitochondrial disorders are often characterized by muscle weakness and fatigue. Null mutations in the heart-muscle adenine nucleotide translocator isoform 1 (ANT1) of both humans and mice cause cardiomyopathy and myopathy associated with exercise intolerance and muscle weakness. Here we d...

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Detalles Bibliográficos
Autores principales:	Schaefer, Patrick M., Huang, Jessica, Butic, Arrienne, Perry, Caroline, Yardeni, Tal, Tan, Wendy, Morrow, Ryan, Baur, Joseph A., Wallace, Douglas C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Brief Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9411682/ https://www.ncbi.nlm.nih.gov/pubmed/35940554 http://dx.doi.org/10.1016/j.molmet.2022.101560

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