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Expression of p16(Ink4a) protein in pleomorphic adenoma and carcinoma ex pleomorphic adenoma proves diversity of tumour biology and predicts clinical course

AIMS: The aim of the study is to correlate p16(Ink4a) expression with the clinical courses of pleomorphic adenoma (PA), its malignant transformation (CaexPA) and treatment outcomes. METHODS: Retrospective analysis (1998–2019) of 47 CaexPA, 148 PA and 22 normal salivary gland samples was performed. P...

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Detalles Bibliográficos
Autores principales: Bartkowiak, Ewelina, Piwowarczyk, Krzysztof, Bodnar, Magdalena, Kosikowski, Paweł, Chou, Jadzia, Woźniak, Aldona, Wierzbicka, Małgorzata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9411887/
https://www.ncbi.nlm.nih.gov/pubmed/33941588
http://dx.doi.org/10.1136/jclinpath-2021-207440