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Randomised controlled trial of fosfomycin in neonatal sepsis: pharmacokinetics and safety in relation to sodium overload

OBJECTIVE: To assess pharmacokinetics and changes to sodium levels in addition to adverse events (AEs) associated with fosfomycin among neonates with clinical sepsis. DESIGN: A single-centre open-label randomised controlled trial. SETTING: Kilifi County Hospital, Kenya. PATIENTS: 120 neonates aged ≤...

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Detalles Bibliográficos
Autores principales:	Obiero, Christina W, Williams, Phoebe, Murunga, Sheila, Thitiri, Johnstone, Omollo, Raymond, Walker, Ann Sarah, Egondi, Thaddaeus, Nyaoke, Borna, Correia, Erika, Kane, Zoe, Gastine, Silke, Kipper, Karin, Standing, Joseph F, Ellis, Sally, Sharland, Mike, Berkley, James Alexander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2022
Materias:	Global Child Health
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9411916/ https://www.ncbi.nlm.nih.gov/pubmed/35078765 http://dx.doi.org/10.1136/archdischild-2021-322483

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