Integrate thermostabilized fusion protein apocytochrome b ( 562 )RIL and N-glycosylation mutations: A novel approach to heterologous expression of human UDP-glucuronosyltransferase (UGT) 2B7

Human UDP-glucuronosyltransferase (UGT) 2B7 is a crucial phase II metabolic enzyme that transfers glucuronic acid from UDP-glucuronic acid (UDPGA) to endobiotic and xenobiotic substrates. Biophysical and biochemical investigations of UGT2B7 are hampered by the challenge of the integral membrane prot...

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Detalles Bibliográficos
Autores principales: Xue, Jia, Zhang, Haitao, Zeng, Su
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9412022/
https://www.ncbi.nlm.nih.gov/pubmed/36034790
http://dx.doi.org/10.3389/fphar.2022.965038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9412022/
https://www.ncbi.nlm.nih.gov/pubmed/36034790
http://dx.doi.org/10.3389/fphar.2022.965038

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