Generation of molecular-targeting helix-loop-helix peptides for inhibition of the interaction between cytotoxic T-lymphocyte-associated protein 4 and B7 in the dog

Blocking the interaction between CD28 and B7 by cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) is a potent immune checkpoint that prevents damage to host tissues from excessive immune responses. However, it also significantly diminishes immune responses against cancers and allows cancer cell g...

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Detalles Bibliográficos
Autores principales: RAMANAYAKE MUDIYANSELAGE, Tharanga MR, FUJIWARA, Daisuke, MICHIGAMI, Masataka, WATANABE, Shunichi, YE, Zhengmao, UEDA, Atsuko, KANEGI, Ryoji, HATOYA, Shingo, FUJII, Ikuo, SUGIURA, Kikuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9412056/
https://www.ncbi.nlm.nih.gov/pubmed/35753760
http://dx.doi.org/10.1292/jvms.21-0318

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