M2 Macrophages promote IL-33 expression, ILC2 expansion and mucous metaplasia in response to early life rhinovirus infections

Wheezing-associated rhinovirus (RV) infections are associated with asthma development. We have shown that infection of immature mice with RV induces type 2 cytokine production and mucous metaplasia which is dependent on IL-33 and type 2 innate lymphoid cells (ILC2s) and intensified by a second heter...

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Detalles Bibliográficos
Autores principales: Han, Mingyuan, Breckenridge, Haley A., Kuo, Shiuhyang, Singh, Shilpi, Goldsmith, Adam G., Li, Yiran, Kreger, Jordan E., Bentley, J. Kelley, Hershenson, Marc B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9412168/
https://www.ncbi.nlm.nih.gov/pubmed/36032072
http://dx.doi.org/10.3389/fimmu.2022.952509

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