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Resveratrol from Dietary Supplement to a Drug Candidate: An Assessment of Potential
Resveratrol (RVT) is a well known phyto-chemical and is widely used in dietary supplements and botanical products. It shows a wide range of pharmacological/beneficial effects. Therefore, it can be a potential candidate to be developed as phyto-pharmaceutical. Multiple diseases are reported to be tre...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9412308/ https://www.ncbi.nlm.nih.gov/pubmed/36015105 http://dx.doi.org/10.3390/ph15080957 |
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author | Khattar, Shivani Khan, Sauban Ahmed Zaidi, Syed Amir Azam Darvishikolour, Mahdi Farooq, Uzma Naseef, Punnoth Poonkuzhi Kurunian, Mohamed Saheer Khan, Mohammed Zaafar Shamim, Athar Khan, Mohd Masih Uzzaman Iqbal, Zeenat Mirza, Mohd. Aamir |
author_facet | Khattar, Shivani Khan, Sauban Ahmed Zaidi, Syed Amir Azam Darvishikolour, Mahdi Farooq, Uzma Naseef, Punnoth Poonkuzhi Kurunian, Mohamed Saheer Khan, Mohammed Zaafar Shamim, Athar Khan, Mohd Masih Uzzaman Iqbal, Zeenat Mirza, Mohd. Aamir |
author_sort | Khattar, Shivani |
collection | PubMed |
description | Resveratrol (RVT) is a well known phyto-chemical and is widely used in dietary supplements and botanical products. It shows a wide range of pharmacological/beneficial effects. Therefore, it can be a potential candidate to be developed as phyto-pharmaceutical. Multiple diseases are reported to be treated by the therapeutic effect of RVT since it has antioxidant, anti-cancer activity and anti-inflammatory activities. It also has a major role in diabetes, arthritis, cardiac disorder and platelet aggregation etc. The major requirements are establishments regarding safety, efficacy profile and physicochemical characterization. As it is already being consumed in variable maximum daily dose, there should not be a major safety concern but the dose needs to be established for different indications. Clinical trials are also being reported in different parts of the world. Physicochemical properties of the moiety are also well reported. Moreover, due to its beneficial effect on health it leads to the development of some intellectual property in the form of patents. |
format | Online Article Text |
id | pubmed-9412308 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-94123082022-08-27 Resveratrol from Dietary Supplement to a Drug Candidate: An Assessment of Potential Khattar, Shivani Khan, Sauban Ahmed Zaidi, Syed Amir Azam Darvishikolour, Mahdi Farooq, Uzma Naseef, Punnoth Poonkuzhi Kurunian, Mohamed Saheer Khan, Mohammed Zaafar Shamim, Athar Khan, Mohd Masih Uzzaman Iqbal, Zeenat Mirza, Mohd. Aamir Pharmaceuticals (Basel) Review Resveratrol (RVT) is a well known phyto-chemical and is widely used in dietary supplements and botanical products. It shows a wide range of pharmacological/beneficial effects. Therefore, it can be a potential candidate to be developed as phyto-pharmaceutical. Multiple diseases are reported to be treated by the therapeutic effect of RVT since it has antioxidant, anti-cancer activity and anti-inflammatory activities. It also has a major role in diabetes, arthritis, cardiac disorder and platelet aggregation etc. The major requirements are establishments regarding safety, efficacy profile and physicochemical characterization. As it is already being consumed in variable maximum daily dose, there should not be a major safety concern but the dose needs to be established for different indications. Clinical trials are also being reported in different parts of the world. Physicochemical properties of the moiety are also well reported. Moreover, due to its beneficial effect on health it leads to the development of some intellectual property in the form of patents. MDPI 2022-08-01 /pmc/articles/PMC9412308/ /pubmed/36015105 http://dx.doi.org/10.3390/ph15080957 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Khattar, Shivani Khan, Sauban Ahmed Zaidi, Syed Amir Azam Darvishikolour, Mahdi Farooq, Uzma Naseef, Punnoth Poonkuzhi Kurunian, Mohamed Saheer Khan, Mohammed Zaafar Shamim, Athar Khan, Mohd Masih Uzzaman Iqbal, Zeenat Mirza, Mohd. Aamir Resveratrol from Dietary Supplement to a Drug Candidate: An Assessment of Potential |
title | Resveratrol from Dietary Supplement to a Drug Candidate: An Assessment of Potential |
title_full | Resveratrol from Dietary Supplement to a Drug Candidate: An Assessment of Potential |
title_fullStr | Resveratrol from Dietary Supplement to a Drug Candidate: An Assessment of Potential |
title_full_unstemmed | Resveratrol from Dietary Supplement to a Drug Candidate: An Assessment of Potential |
title_short | Resveratrol from Dietary Supplement to a Drug Candidate: An Assessment of Potential |
title_sort | resveratrol from dietary supplement to a drug candidate: an assessment of potential |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9412308/ https://www.ncbi.nlm.nih.gov/pubmed/36015105 http://dx.doi.org/10.3390/ph15080957 |
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