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Resveratrol from Dietary Supplement to a Drug Candidate: An Assessment of Potential

Resveratrol (RVT) is a well known phyto-chemical and is widely used in dietary supplements and botanical products. It shows a wide range of pharmacological/beneficial effects. Therefore, it can be a potential candidate to be developed as phyto-pharmaceutical. Multiple diseases are reported to be tre...

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Autores principales: Khattar, Shivani, Khan, Sauban Ahmed, Zaidi, Syed Amir Azam, Darvishikolour, Mahdi, Farooq, Uzma, Naseef, Punnoth Poonkuzhi, Kurunian, Mohamed Saheer, Khan, Mohammed Zaafar, Shamim, Athar, Khan, Mohd Masih Uzzaman, Iqbal, Zeenat, Mirza, Mohd. Aamir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9412308/
https://www.ncbi.nlm.nih.gov/pubmed/36015105
http://dx.doi.org/10.3390/ph15080957
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author Khattar, Shivani
Khan, Sauban Ahmed
Zaidi, Syed Amir Azam
Darvishikolour, Mahdi
Farooq, Uzma
Naseef, Punnoth Poonkuzhi
Kurunian, Mohamed Saheer
Khan, Mohammed Zaafar
Shamim, Athar
Khan, Mohd Masih Uzzaman
Iqbal, Zeenat
Mirza, Mohd. Aamir
author_facet Khattar, Shivani
Khan, Sauban Ahmed
Zaidi, Syed Amir Azam
Darvishikolour, Mahdi
Farooq, Uzma
Naseef, Punnoth Poonkuzhi
Kurunian, Mohamed Saheer
Khan, Mohammed Zaafar
Shamim, Athar
Khan, Mohd Masih Uzzaman
Iqbal, Zeenat
Mirza, Mohd. Aamir
author_sort Khattar, Shivani
collection PubMed
description Resveratrol (RVT) is a well known phyto-chemical and is widely used in dietary supplements and botanical products. It shows a wide range of pharmacological/beneficial effects. Therefore, it can be a potential candidate to be developed as phyto-pharmaceutical. Multiple diseases are reported to be treated by the therapeutic effect of RVT since it has antioxidant, anti-cancer activity and anti-inflammatory activities. It also has a major role in diabetes, arthritis, cardiac disorder and platelet aggregation etc. The major requirements are establishments regarding safety, efficacy profile and physicochemical characterization. As it is already being consumed in variable maximum daily dose, there should not be a major safety concern but the dose needs to be established for different indications. Clinical trials are also being reported in different parts of the world. Physicochemical properties of the moiety are also well reported. Moreover, due to its beneficial effect on health it leads to the development of some intellectual property in the form of patents.
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spelling pubmed-94123082022-08-27 Resveratrol from Dietary Supplement to a Drug Candidate: An Assessment of Potential Khattar, Shivani Khan, Sauban Ahmed Zaidi, Syed Amir Azam Darvishikolour, Mahdi Farooq, Uzma Naseef, Punnoth Poonkuzhi Kurunian, Mohamed Saheer Khan, Mohammed Zaafar Shamim, Athar Khan, Mohd Masih Uzzaman Iqbal, Zeenat Mirza, Mohd. Aamir Pharmaceuticals (Basel) Review Resveratrol (RVT) is a well known phyto-chemical and is widely used in dietary supplements and botanical products. It shows a wide range of pharmacological/beneficial effects. Therefore, it can be a potential candidate to be developed as phyto-pharmaceutical. Multiple diseases are reported to be treated by the therapeutic effect of RVT since it has antioxidant, anti-cancer activity and anti-inflammatory activities. It also has a major role in diabetes, arthritis, cardiac disorder and platelet aggregation etc. The major requirements are establishments regarding safety, efficacy profile and physicochemical characterization. As it is already being consumed in variable maximum daily dose, there should not be a major safety concern but the dose needs to be established for different indications. Clinical trials are also being reported in different parts of the world. Physicochemical properties of the moiety are also well reported. Moreover, due to its beneficial effect on health it leads to the development of some intellectual property in the form of patents. MDPI 2022-08-01 /pmc/articles/PMC9412308/ /pubmed/36015105 http://dx.doi.org/10.3390/ph15080957 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Khattar, Shivani
Khan, Sauban Ahmed
Zaidi, Syed Amir Azam
Darvishikolour, Mahdi
Farooq, Uzma
Naseef, Punnoth Poonkuzhi
Kurunian, Mohamed Saheer
Khan, Mohammed Zaafar
Shamim, Athar
Khan, Mohd Masih Uzzaman
Iqbal, Zeenat
Mirza, Mohd. Aamir
Resveratrol from Dietary Supplement to a Drug Candidate: An Assessment of Potential
title Resveratrol from Dietary Supplement to a Drug Candidate: An Assessment of Potential
title_full Resveratrol from Dietary Supplement to a Drug Candidate: An Assessment of Potential
title_fullStr Resveratrol from Dietary Supplement to a Drug Candidate: An Assessment of Potential
title_full_unstemmed Resveratrol from Dietary Supplement to a Drug Candidate: An Assessment of Potential
title_short Resveratrol from Dietary Supplement to a Drug Candidate: An Assessment of Potential
title_sort resveratrol from dietary supplement to a drug candidate: an assessment of potential
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9412308/
https://www.ncbi.nlm.nih.gov/pubmed/36015105
http://dx.doi.org/10.3390/ph15080957
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