Cargando…

Selenium and Coenzyme Q(10) Intervention Prevents Telomere Attrition, with Association to Reduced Cardiovascular Mortality—Sub-Study of a Randomized Clinical Trial

Short telomeres have been associated with ageing and cardiovascular disease. The influence on leukocyte telomere length (LTL) of long-term intervention with combined selenium and coenzyme Q(10) is unknown. Our aim was to determine whether 42 months of selenium and coenzyme Q(10) supplementation prev...

Descripción completa

Detalles Bibliográficos
Autores principales:	Opstad, Trine Baur, Alexander, Jan, Aaseth, Jan O., Larsson, Anders, Seljeflot, Ingebjørg, Alehagen, Urban
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9412367/ https://www.ncbi.nlm.nih.gov/pubmed/36014852 http://dx.doi.org/10.3390/nu14163346

Ejemplares similares

Increased SIRT1 Concentration Following Four Years of Selenium and Q(10) Intervention Associated with Reduced Cardiovascular Mortality at 10-Year Follow-Up—Sub-Study of a Previous Prospective Double-Blind Placebo-Controlled Randomized Clinical Trial
por: Opstad, Trine Baur, et al.
Publicado: (2023)

Effects of an Intervention with Selenium and Coenzyme Q(10) on Five Selected Age-Related Biomarkers in Elderly Swedes Low in Selenium: Results That Point to an Anti-Ageing Effect—A Sub-Analysis of a Previous Prospective Double-Blind Placebo-Controlled Randomised Clinical Trial
por: Alehagen, Urban, et al.
Publicado: (2023)

Decreased Concentration of Fibroblast Growth Factor 23 (FGF-23) as a Result of Supplementation with Selenium and Coenzyme Q(10) in an Elderly Swedish Population: A Sub-Analysis
por: Alehagen, Urban, et al.
Publicado: (2022)

Decrease in inflammatory biomarker concentration by intervention with selenium and coenzyme Q10: a subanalysis of osteopontin, osteoprotergerin, TNFr1, TNFr2 and TWEAK
por: Alehagen, Urban, et al.
Publicado: (2019)

Dietary Supplementation with Selenium and Coenzyme Q(10) Prevents Increase in Plasma D-Dimer While Lowering Cardiovascular Mortality in an Elderly Swedish Population
por: Alehagen, Urban, et al.
Publicado: (2021)

Supplementation with Selenium and Coenzyme Q10 Reduces Cardiovascular Mortality in Elderly with Low Selenium Status. A Secondary Analysis of a Randomised Clinical Trial
por: Alehagen, Urban, et al.
Publicado: (2016)

Impact of Selenium on Biomarkers and Clinical Aspects Related to Ageing. A Review
por: Alehagen, Urban, et al.
Publicado: (2021)

Selenium and Coenzyme Q10 Supplementation Improves Renal Function in Elderly Deficient in Selenium: Observational Results and Results from a Subgroup Analysis of a Prospective Randomised Double-Blind Placebo-Controlled Trial
por: Alehagen, Urban, et al.
Publicado: (2020)

Significant Changes in Metabolic Profiles after Intervention with Selenium and Coenzyme Q10 in an Elderly Population
por: Alehagen, Urban, et al.
Publicado: (2019)

Significant decrease of von Willebrand factor and plasminogen activator inhibitor-1 by providing supplementation with selenium and coenzyme Q10 to an elderly population with a low selenium status
por: Alehagen, Urban, et al.
Publicado: (2020)

Reduced Cardiovascular Mortality 10 Years after Supplementation with Selenium and Coenzyme Q10 for Four Years: Follow-Up Results of a Prospective Randomized Double-Blind Placebo-Controlled Trial in Elderly Citizens
por: Alehagen, Urban, et al.
Publicado: (2015)

Still reduced cardiovascular mortality 12 years after supplementation with selenium and coenzyme Q10 for four years: A validation of previous 10-year follow-up results of a prospective randomized double-blind placebo-controlled trial in elderly
por: Alehagen, Urban, et al.
Publicado: (2018)

Levels of sP-selectin and hs-CRP Decrease with Dietary Intervention with Selenium and Coenzyme Q10 Combined: A Secondary Analysis of a Randomized Clinical Trial
por: Alehagen, Urban, et al.
Publicado: (2015)

Significant changes in circulating microRNA by dietary supplementation of selenium and coenzyme Q10 in healthy elderly males. A subgroup analysis of a prospective randomized double-blind placebo-controlled trial among elderly Swedish citizens
por: Alehagen, Urban, et al.
Publicado: (2017)

Improved cardiovascular health by supplementation with selenium and coenzyme Q10: applying structural equation modelling (SEM) to clinical outcomes and biomarkers to explore underlying mechanisms in a prospective randomized double-blind placebo-controlled intervention project in Sweden
por: Alehagen, Urban, et al.
Publicado: (2022)

Increase in insulin-like growth factor 1 (IGF-1) and insulin-like growth factor binding protein 1 after supplementation with selenium and coenzyme Q10. A prospective randomized double-blind placebo-controlled trial among elderly Swedish citizens
por: Alehagen, Urban, et al.
Publicado: (2017)

The Aging Kidney—As Influenced by Heavy Metal Exposure and Selenium Supplementation
por: Aaseth, Jan, et al.
Publicado: (2021)

Reduced leukocyte telomere lengths and sirtuin 1 gene expression in long‐term survivors of type 1 diabetes: A Dialong substudy
por: Opstad, Trine Baur, et al.
Publicado: (2020)

The Time Course of Markers of Neutrophil Extracellular Traps in Patients Undergoing Revascularisation for Acute Myocardial Infarction or Stable Angina Pectoris
por: Helseth, Ragnhild, et al.
Publicado: (2016)

Treatment strategies in Alzheimer’s disease: a review with focus on selenium supplementation
por: Aaseth, Jan, et al.
Publicado: (2016)

TERT and TET2 Genetic Variants Affect Leukocyte Telomere Length and Clinical Outcome in Coronary Artery Disease Patients—A Possible Link to Clonal Hematopoiesis
por: Opstad, Trine B., et al.
Publicado: (2022)

Glucose associated NETosis in patients with ST-elevation myocardial infarction: an observational study
por: Helseth, Ragnhild, et al.
Publicado: (2019)

Early Nutritional Interventions with Zinc, Selenium and Vitamin D for Raising Anti-Viral Resistance Against Progressive COVID-19
por: Alexander, Jan, et al.
Publicado: (2020)

The Influence of Autologous Bone Marrow Stem Cell Transplantation on Matrix Metalloproteinases in Patients Treated for Acute ST-Elevation Myocardial Infarction
por: Furenes, Eline Bredal, et al.
Publicado: (2014)

Age‐related telomere attrition causes aberrant gene expression in sub‐telomeric regions
por: Dong, Xiao, et al.
Publicado: (2021)

Circulating levels of IL-18 are significantly influenced by the IL-18 +183 A/G polymorphism in coronary artery disease patients with diabetes type 2 and the metabolic syndrome: an Observational Study
por: Opstad, Trine B, et al.
Publicado: (2011)

The MMP-9 -1562 C/T Polymorphism in the Presence of Metabolic Syndrome Increases the Risk of Clinical Events in Patients with Coronary Artery Disease
por: Opstad, Trine B., et al.
Publicado: (2014)

The Co-Existence of the IL-18+183 A/G and MMP-9 -1562 C/T Polymorphisms Is Associated with Clinical Events in Coronary Artery Disease Patients
por: Opstad, Trine B., et al.
Publicado: (2013)

The influence of CYP 2C19*2 polymorphism on platelet function testing during single antiplatelet treatment with clopidogrel
por: Pettersen, Alf-Aage R, et al.
Publicado: (2011)

Effects of exercise training on markers of adipose tissue remodeling in patients with coronary artery disease and type 2 diabetes mellitus: sub study of the randomized controlled EXCADI trial
por: Zaidi, Hani, et al.
Publicado: (2019)

Markers of remodeling in subcutaneous adipose tissue are strongly associated with overweight and insulin sensitivity in healthy non-obese men
por: Åkra, Sissel, et al.
Publicado: (2020)

Sirtuin1, not NAMPT, possesses anti-inflammatory effects in epicardial, pericardial and subcutaneous adipose tissue in patients with CHD
por: Opstad, Trine Baur, et al.
Publicado: (2023)

Gender differences of polymorphisms in the TF and TFPI genes, as related to phenotypes in patients with coronary heart disease and type-2 diabetes
por: Opstad, Trine B, et al.
Publicado: (2010)

Markers of hypercoagulability in CAD patients. Effects of single aspirin and clopidogrel treatment
por: Bratseth, Vibeke, et al.
Publicado: (2012)

The Time Profile of Pentraxin 3 in Patients with Acute ST-Elevation Myocardial Infarction and Stable Angina Pectoris Undergoing Percutaneous Coronary Intervention
por: Helseth, Ragnhild, et al.
Publicado: (2014)

The Effect of Intracoronary Stem Cell Injection on Markers of Leukocyte Activation in Acute Myocardial Infarction
por: Helseth, Ragnhild, et al.
Publicado: (2015)

Leukocyte telomere length and serum polyunsaturated fatty acids, dietary habits, cardiovascular risk factors and features of myocardial infarction in elderly patients
por: Kalstad, Are A., et al.
Publicado: (2019)

Neutrophil extracellular trap components and myocardial recovery in post-ischemic acute heart failure
por: Langseth, Miriam Sjåstad, et al.
Publicado: (2020)

Atherosclerosis and Coenzyme Q(10)
por: Suárez-Rivero, Juan M., et al.
Publicado: (2019)

Telomere Attrition Due to Infection
por: Ilmonen, Petteri, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_pnuneodpfih77css0avghi0pu8