HMG-CoA Reductase Inhibitor Statins Activate the Transcriptional Activity of p53 by Regulating the Expression of TAZ

Transcriptional coactivator with PDZ-binding motif (TAZ) is a downstream transcriptional regulator of the Hippo pathway that controls cell growth and differentiation. The aberrant activation of TAZ correlates with a poor prognosis in human cancers, such as breast and colon cancers. We previously dem...

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Detalles Bibliográficos
Autores principales: Miyajima, Chiharu, Hayakawa, Yurika, Inoue, Yasumichi, Nagasaka, Mai, Hayashi, Hidetoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9412369/
https://www.ncbi.nlm.nih.gov/pubmed/36015162
http://dx.doi.org/10.3390/ph15081015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9412369/
https://www.ncbi.nlm.nih.gov/pubmed/36015162
http://dx.doi.org/10.3390/ph15081015

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