Unequal Behaviour between Hydrolysable Functions of Nirmatrelvir under Stress Conditions: Structural and Theoretical Approaches in Support of Preformulation Studies

Nirmatrelvir is an antiviral drug approved for the treatment of COVID-19. The available dosage form consists of tablets marketed under the brand name PAXLOVID(®). Although knowledge of nirmatrelvir’s intrinsic stability may be useful for any potential development of other pharmaceutical forms, no da...

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Detalles Bibliográficos
Autores principales: Secretan, Philippe-Henri, Annereau, Maxime, Kini-Matondo, Willy, Prost, Bastien, Prudhomme, Jade, Bournane, Lina, Paul, Muriel, Yagoubi, Najet, Sadou-Yayé, Hassane, Do, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9412384/
https://www.ncbi.nlm.nih.gov/pubmed/36015346
http://dx.doi.org/10.3390/pharmaceutics14081720

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