Phage vB_YenS_P400, a Novel Virulent Siphovirus of Yersinia enterocolitica Isolated from Deer

Phage vB_YenS_P400 isolated from deer, is a virulent siphovirus of Y. enterocolitica, whose circularly permutated genome (46,585 bp) is not substantially related to any other phage deposited in public nucleotide databases. vB_YenS_P400 showed a very narrow host range and exclusively lysed two Y. ent...

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Autores principales: Hammerl, Jens A., Barac, Andrea, Jäckel, Claudia, Fuhrmann, Julius, Gadicherla, Ashish, Hertwig, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9412545/
https://www.ncbi.nlm.nih.gov/pubmed/36014091
http://dx.doi.org/10.3390/microorganisms10081674
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author Hammerl, Jens A.
Barac, Andrea
Jäckel, Claudia
Fuhrmann, Julius
Gadicherla, Ashish
Hertwig, Stefan
author_facet Hammerl, Jens A.
Barac, Andrea
Jäckel, Claudia
Fuhrmann, Julius
Gadicherla, Ashish
Hertwig, Stefan
author_sort Hammerl, Jens A.
collection PubMed
description Phage vB_YenS_P400 isolated from deer, is a virulent siphovirus of Y. enterocolitica, whose circularly permutated genome (46,585 bp) is not substantially related to any other phage deposited in public nucleotide databases. vB_YenS_P400 showed a very narrow host range and exclusively lysed two Y. enterocolitica B4/O:3 strains. Moreover, lytic activity by this phage was only discernible at room temperature. Together with the finding that vB_YenS_P400 revealed a long latent period (90 to 100 min) and low burst size (five to ten), it is not suitable for applications but provides insight into the diversity of Yersinia phages.
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spelling pubmed-94125452022-08-27 Phage vB_YenS_P400, a Novel Virulent Siphovirus of Yersinia enterocolitica Isolated from Deer Hammerl, Jens A. Barac, Andrea Jäckel, Claudia Fuhrmann, Julius Gadicherla, Ashish Hertwig, Stefan Microorganisms Article Phage vB_YenS_P400 isolated from deer, is a virulent siphovirus of Y. enterocolitica, whose circularly permutated genome (46,585 bp) is not substantially related to any other phage deposited in public nucleotide databases. vB_YenS_P400 showed a very narrow host range and exclusively lysed two Y. enterocolitica B4/O:3 strains. Moreover, lytic activity by this phage was only discernible at room temperature. Together with the finding that vB_YenS_P400 revealed a long latent period (90 to 100 min) and low burst size (five to ten), it is not suitable for applications but provides insight into the diversity of Yersinia phages. MDPI 2022-08-19 /pmc/articles/PMC9412545/ /pubmed/36014091 http://dx.doi.org/10.3390/microorganisms10081674 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Hammerl, Jens A.
Barac, Andrea
Jäckel, Claudia
Fuhrmann, Julius
Gadicherla, Ashish
Hertwig, Stefan
Phage vB_YenS_P400, a Novel Virulent Siphovirus of Yersinia enterocolitica Isolated from Deer
title Phage vB_YenS_P400, a Novel Virulent Siphovirus of Yersinia enterocolitica Isolated from Deer
title_full Phage vB_YenS_P400, a Novel Virulent Siphovirus of Yersinia enterocolitica Isolated from Deer
title_fullStr Phage vB_YenS_P400, a Novel Virulent Siphovirus of Yersinia enterocolitica Isolated from Deer
title_full_unstemmed Phage vB_YenS_P400, a Novel Virulent Siphovirus of Yersinia enterocolitica Isolated from Deer
title_short Phage vB_YenS_P400, a Novel Virulent Siphovirus of Yersinia enterocolitica Isolated from Deer
title_sort phage vb_yens_p400, a novel virulent siphovirus of yersinia enterocolitica isolated from deer
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9412545/
https://www.ncbi.nlm.nih.gov/pubmed/36014091
http://dx.doi.org/10.3390/microorganisms10081674
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